日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipid droplet targeting of the lipase coactivator ABHD5 and the fatty liver disease-causing variant PNPLA3 I148M is required to promote liver steatosis.

脂肪酶共激活因子 ABHD5 和导致脂肪肝疾病的变异体 PNPLA3 I148M 靶向脂滴是促进肝脏脂肪变性的必要条件

Teskey Grace, Tiwari Nivedita, Butcko Andrew J, Kumar Amit, Yadav Anuradha, Huang Yu-Ming M, Kelly Christopher V, Granneman James G, Perfield James W, Mottillo Emilio P

Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period

哥廷根小型猪胆碱缺乏、高脂饮食诱发的MASH:特征及饲料逆转期的影响

Hvid, Henning; Hjuler, Sara T; Bedossa, Pierre; Tiniakos, Dina G; Kamzolas, Ioannis; Harder, Lea M; Xue, Yaxin; Perfield, James W; Kirk, Rikke K; Latta, Markus; Mikkelsen, Lars F; Pedersen, Henrik D

Fibroblast growth factor-21 improves insulin action in nonlactating ewes

成纤维细胞生长因子-21改善非哺乳期母羊的胰岛素作用

Lamb, Cassandra L; Giesy, Sarah L; McGuckin, Molly M; Perfield, James W 2nd; Butterfield, Anthony; Moniruzzaman, Mohammed; Haughey, Norman J; McFadden, Joseph W; Boisclair, Yves R

2338 Identifying the genetic determinants of human brown adipose tissue

2338 人类棕色脂肪组织的遗传决定因素鉴定

Antonellis, Patrick J; Droz, Brian A; Cosgrove, Richard; O'Farrell, Libbey S; Coskun, Tamer; Perfield, James W 2nd; Bauer, Steven; Wade, Mark; Chouinard, Tara E; Brozinick, Joseph T; Adams, Andrew C; Samms, Ricardo J; Becher, Tobias; Cohen, Paul; Wibmer, Andreas; Kramer, Daniel J

Fibroblast growth factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic peroxisome proliferator-activated receptor γ coactivator-1α-deficient mice

成纤维细胞生长因子21可提高肝脏氧化能力,但不会增加肝脏过氧化物酶体增殖物激活受体γ共激活因子-1α缺陷小鼠的体力活动或能量消耗。

Fletcher, Justin A; Linden, Melissa A; Sheldon, Ryan D; Meers, Grace M; Morris, E Matthew; Butterfield, Anthony; Perfield, James W 2nd; Rector, R Scott; Thyfault, John P

FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans

FGF21是成人体内一种胰岛素依赖性餐后激素

Samms, Ricardo J; Lewis, Jo E; Norton, Luke; Stephens, Francis B; Gaffney, Christopher J; Butterfield, Tony; Smith, Dennis P; Cheng, Christine C; Perfield, James W 2nd; Adams, Andrew C; Ebling, Francis J P; Tsintzas, Kostas

Effect of circulating glucagon and free fatty acids on hepatic FGF21 production in dairy cows

循环胰高血糖素和游离脂肪酸对奶牛肝脏FGF21产生的影响

Caixeta, Luciano S; Giesy, Sarah L; Krumm, Christopher S; Perfield, James W Nd; Butterfield, Anthony; Schoenberg, Katie M; Beitz, Donald C; Boisclair, Yves R

Transcriptomic differences in intra-abdominal adipose tissue in extremely obese adolescents with different stages of NAFLD

极度肥胖青少年不同阶段非酒精性脂肪性肝病患者腹腔内脂肪组织的转录组差异

Sheldon, Ryan D; Kanosky, Kayla M; Wells, Kevin D; Miles, Lili; Perfield, James W 2nd; Xanthakos, Stavra; Inge, Thomas H; Rector, R Scott

Unique transcriptomic signature of omental adipose tissue in Ossabaw swine: a model of childhood obesity

奥萨博猪网膜脂肪组织独特的转录组特征:一种儿童肥胖模型

Toedebusch, Ryan G; Roberts, Michael D; Wells, Kevin D; Company, Joseph M; Kanosky, Kayla M; Padilla, Jaume; Jenkins, Nathan T; Perfield, James W 2nd; Ibdah, Jamal A; Booth, Frank W; Rector, R Scott

Altered hepatic lipid metabolism contributes to nonalcoholic fatty liver disease in leptin-deficient Ob/Ob mice

肝脏脂质代谢异常是瘦素缺乏型 Ob/Ob 小鼠非酒精性脂肪肝疾病的致病因素之一。

Perfield, James W 2nd; Ortinau, Laura C; Pickering, R Taylor; Ruebel, Meghan L; Meers, Grace M; Rector, R Scott