日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-informed design of an ultrabright RNA-activated fluorophore

基于结构的超亮RNA激活荧光团设计

Yang, Mo; Prestwood, Peri R; Passalacqua, Luiz F M; Balaratnam, Sumirtha; Fullenkamp, Christopher R; Arney, J Winston; Weeks, Kevin M; Ferre-D'Amare, Adrian; Schneekloth, John S Jr

Machine Learning-Augmented Molecular Dynamics Simulations (MD) Reveal Insights Into the Disconnect Between Affinity and Activation of ZTP Riboswitch Ligands

机器学习增强的分子动力学模拟(MD)揭示了ZTP核糖开关配体亲和力和激活之间脱节的机制

Fullenkamp, Christopher R; Mehdi, Shams; Jones, Christopher P; Tenney, Logan; Pichling, Patricio; Prestwood, Peri R; Ferré-D'Amaré, Adrian R; Tiwary, Pratyush; Schneekloth, John S

Sensory neuronal mTORC1 signaling establishes neuroimmune memory that initiates allergic immunity

感觉神经元 mTORC1 信号传导建立神经免疫记忆,从而启动过敏免疫。

Zhu, Xueping; Yang, Haibo; Zhan, Haoting; Kernin, Isabela J; Le, Ngoc; Buttaci, Dean R; Han, Cai; Naik, Parth R; Altenburger, Lukas M; Wu, Elena; Matatia, Peri R; Zaghouani, Sarah; Smith, Neal P; Londoner, Rebecca; Flayer, Cameron H; Sun, Zhengwang; Villani, Alexandra-Chloe; Rahimi, Rod A; Sokol, Caroline L

Discovery of small molecule probes targeting the 5' stem-loop in the yeast U4/U6 snRNA

发现靶向酵母U4/U6 snRNA 5'茎环的小分子探针

Yang, Mo; Parmar, Shaifaly; Balaratnam, Sumirtha; Bume, Desta D; Prestwood, Peri R; Kasprzak, Wojciech K; Schneekloth, John S Jr

A γδ T cell-IL-3 axis controls allergic responses through sensory neurons

γδ T细胞-IL-3轴通过感觉神经元控制过敏反应

Cameron H Flayer ,Isabela J Kernin # ,Peri R Matatia # ,Xiangsunze Zeng ,David A Yarmolinsky ,Cai Han ,Parth R Naik ,Dean R Buttaci ,Pamela A Aderhold ,Ryan B Camire ,Xueping Zhu ,Alice J Tirard ,John T McGuire ,Neal P Smith ,Clive S McKimmie ,Cameron S McAlpine ,Filip K Swirski ,Clifford J Woolf ,Alexandra-Chloe Villani ,Caroline L Sokol

Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression

对核糖开关配体相互作用的机制分析为基因表达的药理学调控提供了新的见解

Parmar, Shaifaly; Bume, Desta Doro; Connelly, Colleen M; Boer, Robert E; Prestwood, Peri R; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth, John S Jr

Sensory sentinels: Neuroimmune detection and food allergy

感觉哨兵:神经免疫检测和食物过敏

Matatia, Peri R; Christian, Elena; Sokol, Caroline L

Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression

核糖开关配体相互作用的机制分析为基因表达的药理学调控提供了新的见解

Parmar, Shaifaly; Bume, Desta Doro; Conelly, Colleen; Boer, Robert; Prestwood, Peri R; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth, John S Jr

Neighboring inteins interfere with one another's homing capacity

相邻的内含子会干扰彼此的归巢能力

Israela Turgeman-Grott, Danielle Arsenault, Dekel Yahav, Yutian Feng, Guy Miezner, Doron Naki, Omri Peri, R Thane Papke, Johann Peter Gogarten, Uri Gophna

Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation

在混合炎症期间,干扰素γ限制了2型淋巴细胞微环境的边界。

Kelly M Cautivo ,Peri R Matatia ,Carlos O Lizama ,Nicholas M Mroz ,Madelene W Dahlgren ,Xiaofei Yu ,Julia Sbierski-Kind ,Marcela T Taruselli ,Jeremy F Brooks ,Adam Wade-Vallance ,Sofia E Caryotakis ,Anthony A Chang ,Hong-Erh Liang ,Julie Zikherman ,Richard M Locksley ,Ari B Molofsky