Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
hMLH1基因通过表观遗传基因沉默发生双等位基因失活,这是导致人类微卫星不稳定性(MSI)癌症的一种新机制。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.95.15.8698
Veigl, M L; Kasturi, L; Olechnowicz, J; Ma, A H; Lutterbaugh, J D; Periyasamy, S; Li, G M; Drummond, J; Modrich, P L; Sedwick, W D; Markowitz, S D