日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preliminary Safety and Efficacy of Navitoclax Plus Ruxolitinib in Janus Kinase Inhibitor-Naïve Patients With Myelofibrosis From the Multicenter, Open-Label, Phase 2 Study (REFINE)

来自多中心、开放标签、II期研究(REFINE)的Navitoclax联合Ruxolitinib治疗未接受过Janus激酶抑制剂治疗的骨髓纤维化患者的初步安全性和有效性

Passamonti, Francesco; Foran, James M; Tandra, Anand; De Stefano, Valerio; Fox, Maria Laura; Mattour, Ahmad; McMullin, Mary Frances; Perkins, Andrew C; Rodriguez-Macías, Gabriela; Sibai, Hassan A; Polepally, Akshanth R; Sun, Yan; Chopra, Avijeet S; Harb, Jason G; Qin, Qin; Potluri, Jalaja; How, Jonathan

Reduced PI3K(p110α) induces atrial myopathy, and PI3K-related lipids are dysregulated in athletes with atrial fibrillation

PI3K(p110α)减少会诱发心房肌病,并且PI3K相关脂质在患有心房颤动的运动员中失调。

Bass-Stringer, Sebastian; Bernardo, Bianca C; Yildiz, Gunes S; Matsumoto, Aya; Kiriazis, Helen; Harmawan, Claudia A; Tai, Celeste M K; Chooi, Roger; Bottrell, Lauren; Ezeani, Martin; Donner, Daniel G; D'Elia, Aascha A; Ooi, Jenny Y Y; Mellett, Natalie A; Luo, Jieting; Masterman, Emma I; Janssens, Kristel; Olshansky, Gavriel; Howden, Erin J; Cross, Jonathon H; Hagemeyer, Christoph E; Lin, Ruby C Y; Thomas, Colleen J; Magor, Graham W; Perkins, Andrew C; Marwick, Thomas H; Kawakami, Hiroshi; Meikle, Peter J; Greening, David W; Weeks, Kate L; La Gerche, André; Tham, Yow Keat; McMullen, Julie R

KLF feedback loops in innate immunity

先天免疫中的KLF反馈回路

Salmon, Jessica M; Adams, Holly; Magor, Graham W; Perkins, Andrew C

Clinical utility of panel-based genetic sequencing for von Willebrand disease

基于基因组测序的血管性血友病临床应用价值

Ramanan, Radha; Van Laer, Christine; Baert, Sarissa; Kint, Cyrielle; Van Geet, Chris; Van Thillo, Quentin; Verhamme, Peter; Vanassche, Thomas; McFadyen, James D; Perkins, Andrew C; Tran, Huyen A; Labarque, Veerle; Freson, Kathleen

Real World Management of Cytopenias and Infections in Patients With Myelofibrosis Treated With Ruxolitinib

鲁索替尼治疗骨髓纤维化患者细胞减少症和感染的真实世界管理

Butler, Liesl A; Forsyth, Cecily; Harrison, Claire; Perkins, Andrew C

Congenital Anemia Phenotypes Due to KLF1 Mutations

KLF1基因突变引起的先天性贫血表型

Perkins, Andrew C; Bieker, James

Clinical acceleration of JAK2 p.V617F driven myeloproliferative disease due to a new uncommon homozygous MPL p.Y591D mutation

由一种罕见的纯合MPL p.Y591D突变引起的JAK2 p.V617F驱动的骨髓增生性疾病的临床进展加速

Ong, Jeremy; Lin, Jane I; Mitchell, Helen; Morgan, Susan; Perkins, Andrew C

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

KLF/SP转录因子中显性新功能突变的基础是DNA结合特异性的破坏和异位转录。

Ilsley, Melissa D; Huang, Stephen; Magor, Graham W; Landsberg, Michael J; Gillinder, Kevin R; Perkins, Andrew C

JAK1 somatic mutation in a myeloproliferative neoplasm

骨髓增生性肿瘤中的JAK1体细胞突变

Arulogun, Suzanne O; Choong, Hock-Lai; Taylor, Debbie; Ambrosoli, Paula; Magor, Graham; Irving, Ian M; Keng, Tee-Beng; Perkins, Andrew C

High resolution temporal transcriptomics of mouse embryoid body development reveals complex expression dynamics of coding and noncoding loci

小鼠胚状体发育的高分辨率时间转录组学揭示了编码和非编码基因位点的复杂表达动态

Gloss, Brian S; Signal, Bethany; Cheetham, Seth W; Gruhl, Franziska; Kaczorowski, Dominik C; Perkins, Andrew C; Dinger, Marcel E