日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dnmt3a-dependent de novo DNA methylation enforces lineage commitment and preserves functionality of memory Th1 and Tfh cells

Dnmt3a依赖的从头DNA甲基化强化谱系定向并维持记忆性Th1和Tfh细胞的功能。

Perkins, Bryant; Novis, Camille L; Baessler, Andrew; Sircy, Linda M; Thomas, Monyca M; Harrison-Chau, Malia; Richens, Andrew W; Fuchs, Bryce; Nguyen, Nguyen X; Flint, Kaitlyn; Winter, Brittany S; Varley, Katherine E; Hale, J Scott

Identifying the master regulator Bcl6 and its archrival Blimp1 for T follicular helper lineage differentiation

鉴定T滤泡辅助细胞谱系分化的主调控因子Bcl6及其主要竞争对手Blimp1

Perkins, Bryant; Hale, J Scott

OCA-B/Pou2af1 is sufficient to promote CD4(+) T cell memory and prospectively identifies memory precursors.

OCA-B/Pou2af1 足以促进 CD4(+) T 细胞记忆,并能前瞻性地识别记忆前体

Sun Wenxiang, Hughes Erik P, Kim Heejoo, Perovanovic Jelena, Charley Krystal R, Perkins Bryant, Du Junhong, Ibarra Andrea, Syage Amber R, Hale J Scott, Williams Matthew A, Tantin Dean

Tet2 deletion in CD4+ T cells disrupts Th1 lineage commitment in memory cells and enhances T follicular helper cell recall responses to viral rechallenge

CD4+ T 细胞中 Tet2 的缺失会破坏记忆细胞中 Th1 谱系的分化,并增强滤泡辅助性 T 细胞对病毒再次感染的记忆反应。

Baessler, Andrew; Fuchs, Bryce; Perkins, Bryant; Richens, Andrew W; Novis, Camille L; Harrison-Chau, Malia; Sircy, Linda M; Thiede, Kendall A; Hale, J Scott

Improved therapeutic index of an acidic pH-selective antibody

提高酸性pH选择性抗体的治疗指数

Peter S Lee ,Katherine G MacDonald ,Evan Massi ,Pamela V Chew ,Christine Bee ,Padma Perkins ,Bryant Chau ,Kent Thudium ,Jack Lohre ,Pradyot Nandi ,Ekaterina G Deyanova ,Ishita Barman ,Olafur Gudmundsson ,Gavin Dollinger ,Tim Sproul ,John J Engelhardt ,Pavel Strop ,Arvind Rajpal