日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Domain-specific AI segmentation of IMPDH2 rod/ring structures in mouse embryonic stem cells.

小鼠胚胎干细胞中 IMPDH2 棒状/环状结构的特定领域 AI 分割

Ball Samuel T M, Hennessy Meagan J, Tan Yuhan, Hoettges Kai F, Perkins Neil D, Wilkinson David J, White Michael R H, Zheng Yalin, Turner David A

c-Rel-dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

c-Rel依赖的Chk2信号通路调控DNA损伤反应,从而限制肝癌的发生。

Leslie, Jack; Hunter, Jill E; Collins, Amy; Rushton, Amelia; Russell, Lauren G; Ramon-Gil, Erik; Laszczewska, Maja; McCain, Misti; Zaki, Marco Y W; Knox, Amber; Seow, Yixin; Sabater, Laura; Geh, Daniel; Perkins, Neil D; Reeves, Helen L; Tiniakos, Dina; Mann, Derek A; Oakley, Fiona

Induction of the immunoprotective coat of Yersinia pestis at body temperature is mediated by the Caf1R transcription factor.

鼠疫耶尔森菌在体温下免疫保护性外壳的诱导是由 Caf1R 转录因子介导的

Al-Jawdah Abdulmajeed D, Ivanova Iglika G, Waller Helen, Perkins Neil D, Lakey Jeremy H, Peters Daniel T

More than just an IκB kinase: the IKK complex coordinates mRNA stability and transcription

IKK复合物不仅仅是IκB激酶:它还协调mRNA的稳定性和转录。

Perkins, Neil D

c-Rel and its many roles in cancer: an old story with new twists

c-Rel及其在癌症中的多种作用:一个老故事的新转折

Hunter, Jill E; Leslie, Jack; Perkins, Neil D

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphoma

临床开发候选药物 CCT245737 是一种口服活性 CHK1 抑制剂,在 RAS 突变型非小细胞肺癌和 Eµ-MYC 驱动的 B 细胞淋巴瘤中显示出临床前活性。

Walton, Mike I; Eve, Paul D; Hayes, Angela; Henley, Alan T; Valenti, Melanie R; De Haven Brandon, Alexis K; Box, Gary; Boxall, Kathy J; Tall, Matthew; Swales, Karen; Matthews, Thomas P; McHardy, Tatiana; Lainchbury, Michael; Osborne, James; Hunter, Jill E; Perkins, Neil D; Aherne, G Wynne; Reader, John C; Raynaud, Florence I; Eccles, Suzanne A; Collins, Ian; Garrett, Michelle D

Heme regulates gene expression by triggering Crm1-dependent nuclear export of Bach1

血红素通过触发 Crm1 依赖的 Bach1 核输出来调节基因表达。

Barré, Benjamin; Perkins, Neil D; Suzuki, Hiroshi; Tashiro, Satoshi; Hira, Shusuke; Sun, Jiying; Yamazaki, Chikara; Zenke, Yukari; Ikeda-Saito, Masao; Yoshida, Minoru; Igarashi, Kazuhiko

Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence

敌友难辨:活化B细胞核因子κB轻链增强子在细胞衰老中的新兴作用

Mowla, Sophia N; Perkins, Neil D; Jat, Parmjit S

The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration

RelA (p65) 苏氨酸 505 位点磷酸化在细胞生长、存活和迁移调控中的作用

Msaki, Aichi; Sánchez, Ana M; Koh, Li Fang; Barré, Benjamin; Rocha, Sonia; Perkins, Neil D; Johnson, Renée F

A cell cycle regulatory network controlling NF-kappaB subunit activity and function

控制 NF-κB 亚基活性和功能的细胞周期调控网络

Barré, Benjamin; Perkins, Neil D