Perkumas相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Endothelial cell stiffness and type drive the formation of biomechanically induced transcellular pores

内皮细胞的硬度和类型驱动生物力学诱导的跨细胞孔的形成

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2025.116668

Siadat, Seyed Mohammad; Li, Haiyan; Millette, Brigid; Safa, Babak N; Wong, Cydney A; Bahrani Fard, M Reza; Braakman, Sietse T; Tay, Ian; Bertrand, Jacques A; Read, A Thomas; Schildmeyer, Lisa; Perkumas, Kristin M; Stamer, W Daniel; Overby, Darryl R; Ethier, C Ross

细胞生物学

发表日期：2026

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Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells

糖皮质激素诱导的人类小梁网和施莱姆氏管细胞转录组随时间的变化

期刊:Investigative Ophthalmology & Visual Science

影响因子:4.7

doi:10.1167/iovs.67.2.13

Mehrotra, Sudeep; Jeanneret, Haven; Perkumas, Kristin; Liu, Renee; Lama, Jyoti; Huynh, Katie; Mukundan, Ananya; Scott, Hilary; Apivatthakakul, Atitaya; Wiggs, Janey L; Sobrin, Lucia; Stamer, W Daniel; Segrè, Ayellet V

细胞生物学

免疫/内分泌

发表日期：2026

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Expression changes of human Schlemm's canal endothelial cells in response to cyclic mechanical stretch

人施莱姆氏管内皮细胞对周期性机械拉伸的表达变化

期刊:Experimental Eye Research

影响因子:2.7

doi:10.1016/j.exer.2025.110747

Heo, Yejin; Cai, Jingwen; Perkumas, Kristin; Aboobakar, Inas F; Stamer, W Daniel; Liu, Yutao

细胞生物学

发表日期：2026

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Time-dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal

糖皮质激素诱导的人类小梁网和施莱姆氏管转录组随时间的变化

doi:10.64898/2025.12.31.696882

Mehrotra, Sudeep; Jeanneret, Haven; Perkumas, Kristin; Liu, Renee; Lama, Jyoti; Huynh, Katie; Mukundan, Ananya; Scott, Hilary; Apivatthakakul, Atitaya; Wiggs, Janey L; Sobrin, Lucia; Stamer, W Daniel; Segrè, Ayellet V

免疫/内分泌

发表日期：2026

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Endothelial cell-specific postnatal deletion of Nos3 preserves intraocular pressure homeostasis via macrophage recruitment and NOS2 upregulation

出生后内皮细胞特异性敲除Nos3可通过巨噬细胞募集和NOS2上调来维持眼内压稳态。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI183440

Kelly, Ruth A; Kuhn, Megan S; Reina-Torres, Ester; Balasubramanian, Revathi; Perkumas, Kristin M; Li, Guorong; Takahashi, Takamune; John, Simon Wm; Elliott, Michael H; Overby, Darryl R; Stamer, W Daniel

细胞生物学

免疫/内分泌

发表日期：2025

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TRPV4 modulates substrate stiffness mechanosensing and transcellular pore formation in human Schlemm's canal cells.

TRPV4 调节人类 Schlemm 管细胞的基质刚度机械感知和跨细胞孔形成

doi:10.1101/2025.05.25.656000

Li Haiyan, Wong Cydney, Siadat Seyed Mohammad, Perkumas Kristin M, Bertrand Jacques A, Overby Darryl R, Sulchek Todd, Stamer W Daniel, Ethier C Ross

细胞生物学

发表日期：2025

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Endothelial cell stiffness and type drive the formation of biomechanically-induced transcellular pores.

内皮细胞的硬度和类型决定了生物力学诱导的跨细胞孔的形成

doi:10.1101/2024.10.23.619950

Siadat Seyed Mohammad, Li Haiyan, Millette Brigid A, Safa Babak N, Wong Cydney A, Bahrani Fard M Reza, Braakman Sietse T, Tay Ian, Bertrand Jacques A, Read A Thomas, Schildmeyer Lisa A, Perkumas Kristin M, Stamer W Daniel, Overby Darryl R, Ethier C Ross

细胞生物学

发表日期：2024

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Proposed Mechanism of Long-Term Intraocular Pressure Lowering With the Bimatoprost Implant

比马前列素植入物长期降低眼内压的可能机制

期刊:Investigative Ophthalmology & Visual Science

影响因子:4.7

doi:10.1167/iovs.64.3.15

Stamer, W Daniel; Perkumas, Kristin M; Kang, Min H; Dibas, Mohammed; Robinson, Michael R; Rhee, Douglas J

发表日期：2023

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Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells

赖氨酸氧化酶样 1-反义 1 (LOXL1-AS1) lncRNA 差异调节人类眼部细胞的基因和蛋白质表达、信号传导和形态

期刊:Human Molecular Genetics

影响因子:3.1

doi:10.1093/hmg/ddad128

Heather M Schmitt, Kristyn M Hake, Kristin M Perkumas, Brandon M Lê, Maria F Suarez, Michael L De Ieso, Rashad S Rahman, William M Johnson, María Gomez-Caraballo, Allison E Ashley-Koch, Michael A Hauser, W Daniel Stamer

细胞生物学

发表日期：2023

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Shear stress induces autophagy in Schlemm's canal cells via primary cilia-mediated SMAD2/3 signaling pathway

剪切应力通过初级纤毛介导的 SMAD2/3 信号通路诱导 Schlemm 管细胞自噬

期刊:Autophagy Reports

doi:10.1080/27694127.2023.2236519

Myoung Sup Shim, Angela Dixon, April Nettesheim, Kristin M Perkumas, W Daniel Stamer, Yang Sun, Paloma B Liton

细胞生物学

发表日期：2023

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