A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans
TMPRSS6抑制剂单克隆抗体可改善β-地中海贫血小鼠模型中的疾病症状，并降低健康人体内铁含量。
期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.191813
Lob, Heinrich E; Singh, Nikhil; Mohammadi, Kusha; Ivanova, Larisa; Crowell, Beth; Kim, Hyon J; Kravets, Leah; Das, Nanditha M; Ray, Yonaton; Kim, Jee Hae; Rottey, Sylvie; Labriola-Tompkins, Emily; Hassan, Hazem E; Farrelly, Lorna; Chin, Harvey F; Preda, Marilena; Spencer Noakes, Leigh; Saotome, Kei; Franklin, Matthew; Retter, Marc W; Karayusuf, Elif; Flanagan, John J; Olson, William; Nannuru, Kalyan C; Idone, Vincent; Burczynski, Michael E; Harari, Olivier A; Perlee, Lorah; Van Lancker, Griet; Murphy, Andrew J; Economides, Aris N; Hatsell, Sarah J
