Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health.
TMEM106B 水平升高会导致溶酶体功能障碍，从而影响突触信号传导和神经元健康
期刊:Molecular Neurodegeneration
影响因子:17.5
doi:10.1186/s13024-025-00831-2
Perneel Jolien, Lastra Osua Miranda, Alidadiani Sara, Peeters Nele, De Witte Linus, Heeman Bavo, Manzella Simona, De Rycke Riet, Brooks Mieu, Perkerson Ralph B, Calus Elke, De Coster Wouter, Neumann Manuela, Mackenzie Ian R A, Van Dam Debby, Asselbergh Bob, Ellender Tommas, Zhou Xiaolai, Rademakers Rosa
