Pernow John相关文献与解析，生知库 | 链接生命科学的每一步

Picozzi Gaia, Westerberg Leo J S, Jurga Juliane, Zeberg Hugo, Nihlen Carina, Pernow John, CarlstrÃ¶m Mattias, Weitzberg Eddie, Ã gren Richard, Lundberg Jon O

Human

发表日期：2026

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Targeting Arginase 1 but Not Arginase 2 Protects from Myocardial Ischemia-Reperfusion Injury via Nitric Oxide Signaling by Red Blood Cells in Type 2 Diabetes

靶向精氨酸酶1而非精氨酸酶2可通过红细胞一氧化氮信号通路保护2型糖尿病患者免受心肌缺血再灌注损伤

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox15010058

Yang, Jiangning; Tratsiakovich, Yahor; Cao, Renhai; Mahdi, Ali; Pironti, Gianluigi; Jiao, Tong; Humoud, Rawan; Kontidou, Eftychia; Tengbom, John; Collado, Aida; Zhou, Zhichao; Cao, Yihai; Köhler, Eleonore; Mullick, Adam E; Pernow, John

microRNA-210 in red blood cells differentially regulates vascular endothelial function between type 1 and type 2 diabetes.

红细胞中的 microRNA-210 对 1 型糖尿病和 2 型糖尿病患者的血管内皮功能具有不同的调节作用。

期刊:Physiological Reports

影响因子:1.9

doi:10.14814/phy2.70789

Jiao Tong, Tengbom John, Kontidou Eftychia, Santana-Garrido Ãlvaro, Humoud Rawan, Alvarsson Michael, Manickam Kesavan, Yang Jiangning, Mahdi Ali, Collado Aida, Pernow John, Zhou Zhichao

Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes.

红细胞衍生的细胞外囊泡通过精氨酸酶-1和氧化应激诱导2型糖尿病内皮功能障碍

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI180900

Collado Aida, Humoud Rawan, Kontidou Eftychia, Eldh Maria, Swaich Jasmin, Zhao Allan, Yang Jiangning, Jiao Tong, Domingo Elena, CarlestÃ¥l Emelie, Mahdi Ali, Tengbom John, VÃ©gvÃ¡ri Ãkos, Deng Qiaolin, Alvarsson Michael, Gabrielsson Susanne, Eriksson Per, Zhou Zhichao, Pernow John

Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolically healthy offspring.

母体糖尿病会导致代谢健康的后代出现性别二态性的早发性心血管功能障碍。

期刊:Cell Reports Medicine

影响因子:10.6

doi:10.1016/j.xcrm.2025.102454

Zhao Allan, Wei Yuxia, Kontidou Eftychia, Mahdi Ali, Jannig Paulo R, Torstensson Sara, Jiang Hong, Larsson Alice, Collado Aida, Humoud Rawan, GrÃ¼nler Jacob, ErsgÃ¥rd David, Esen Buket ÃztÃ¼rk, Zheng Xiaowei, Lu Haojiang, Lindgren Eva, Risal Sanjiv, Zhao Jian, Stener-Victorin Elisabet, SÃ¸rensen Henrik Toft, Pedersen Lars, Pernow John, Zhou Zhichao, Carlsson Sofia, Catrina Sergiu-Bogdan, Deng Qiaolin

The size of myocardial infarction and peri-infarction edema are not major determinants of diastolic impairment after acute myocardial infarction

心肌梗死面积和梗死周围水肿并非急性心肌梗死后舒张功能障碍的主要决定因素。

期刊:

影响因子:

doi:10.1007/s10554-024-03294-6

Sundqvist, Martin G; Verouhis, Dinos; Sörensson, Peder; Henareh, Loghman; Persson, Jonas; Saleh, Nawzad; Settergren, Magnus; Witt, Nils; Böhm, Felix; Pernow, John; Tornvall, Per; Ugander, Martin

Differences in endothelial function between patients with Type 1 and Type 2 diabetes: effects of red blood cells and arginase

型糖尿病和 2 型糖尿病患者内皮功能的差异：红细胞和精氨酸酶的影响

期刊:Clinical Science

影响因子:7.7

doi:10.1042/CS20240447

Tengbom, John; Kontidou, Eftychia; Collado, Aida; Yang, Jiangning; Alvarsson, Michael; Brinck, Jonas; Rössner, Sophia; Zhou, Zhichao; Pernow, John; Mahdi, Ali

Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP

缺氧红细胞通过激活可溶性鸟苷酸环化酶和释放环磷酸鸟苷（cGMP）发挥心脏保护作用。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI167693

Yang, Jiangning; Sundqvist, Michaela L; Zheng, Xiaowei; Jiao, Tong; Collado, Aida; Tratsiakovich, Yahor; Mahdi, Ali; Tengbom, John; Mergia, Evanthia; Catrina, Sergiu-Bogdan; Zhou, Zhichao; Carlström, Mattias; Akaike, Takaaki; Cortese-Krott, Miriam M; Weitzberg, Eddie; Lundberg, Jon O; Pernow, John

Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 syndrome with and without postural orthostatic tachycardia syndrome: a multi-omic profiling study

COVID-19 急性后期综合征（伴或不伴体位性心动过速综合征）中止血、代谢、免疫反应和血管生成失调：一项多组学分析研究

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-023-47539-1

Mahdi, Ali; Zhao, Allan; Fredengren, Emelie; Fedorowski, Artur; Braunschweig, Frieder; Nygren-Bonnier, Malin; Runold, Michael; Bruchfeld, Judith; Nickander, Jannike; Deng, Qiaolin; Checa, Antonio; Desta, Liyew; Pernow, John; Ståhlberg, Marcus

Dyssynchrony and resynchronization in heart failure-effects on regional and global gene expression in a murine pacemaker model

心力衰竭中的不同步和再同步——对小鼠起搏器模型中区域和整体基因表达的影响

期刊:European Heart Journal Open

影响因子:

doi:10.1093/ehjopen/oead058

Ståhlberg, Marcus; Rullman, Eric; Pernow, John; Nakagawa, Ryo; Nordin, Hugo; Braunschweig, Frieder; Ljung, Karin

The sodium/iodide symporter is a nitrate transporter in the human salivary gland.

钠/碘同向转运蛋白是人类唾液腺中的硝酸盐转运蛋白。

Targeting Arginase 1 but Not Arginase 2 Protects from Myocardial Ischemia-Reperfusion Injury via Nitric Oxide Signaling by Red Blood Cells in Type 2 Diabetes

靶向精氨酸酶1而非精氨酸酶2可通过红细胞一氧化氮信号通路保护2型糖尿病患者免受心肌缺血再灌注损伤

microRNA-210 in red blood cells differentially regulates vascular endothelial function between type 1 and type 2 diabetes.

红细胞中的 microRNA-210 对 1 型糖尿病和 2 型糖尿病患者的血管内皮功能具有不同的调节作用。

Erythrocyte-derived extracellular vesicles induce endothelial dysfunction through arginase-1 and oxidative stress in type 2 diabetes.

红细胞衍生的细胞外囊泡通过精氨酸酶-1和氧化应激诱导2型糖尿病内皮功能障碍

Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolically healthy offspring.

母体糖尿病会导致代谢健康的后代出现性别二态性的早发性心血管功能障碍。

The size of myocardial infarction and peri-infarction edema are not major determinants of diastolic impairment after acute myocardial infarction

心肌梗死面积和梗死周围水肿并非急性心肌梗死后舒张功能障碍的主要决定因素。

Differences in endothelial function between patients with Type 1 and Type 2 diabetes: effects of red blood cells and arginase

型糖尿病和 2 型糖尿病患者内皮功能的差异：红细胞和精氨酸酶的影响

Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP

缺氧红细胞通过激活可溶性鸟苷酸环化酶和释放环磷酸鸟苷（cGMP）发挥心脏保护作用。

Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 syndrome with and without postural orthostatic tachycardia syndrome: a multi-omic profiling study

COVID-19 急性后期综合征（伴或不伴体位性心动过速综合征）中止血、代谢、免疫反应和血管生成失调：一项多组学分析研究

Dyssynchrony and resynchronization in heart failure-effects on regional and global gene expression in a murine pacemaker model

心力衰竭中的不同步和再同步——对小鼠起搏器模型中区域和整体基因表达的影响