日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Retinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models.

使用双AAV内含子载体的视网膜基因疗法治疗Stargardt病在大动物模型中安全有效

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adt9354
Ferla Rita, Pugni Eugenio, Lupo Mariangela, Tiberi Paola, Fioretto Federica, Perota Andrea, Duchi Roberto, Lagutina Irina, Gesualdo Carlo, Rossi Settimio, Ventrella Domenico, Elmi Alberto, McClinton Benjamin, Toomes Carmel, Xu Tongzhou, Molday Robert S, Surace Enrico M, Simonelli Francesca, Bacci Maria L, Galli Cesare, Memon Muhammad A, Shams Naveed, Auricchio Alberto, Trapani Ivana
发表日期：2025
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Transabdominal ultrasound guided AAV9-GFP delivery in fetal pigs: a translational and minimally invasive model for in utero fetal gene therapy.

经腹部超声引导 AAV9-GFP 递送至胎猪：一种用于子宫内胎儿基因治疗的转化和微创模型。

期刊:Gene Therapy
影响因子:4.5
doi:10.1038/s41434-025-00551-8
Di Donfrancesco Alessia, Adelizzi Alessia, Giri Anastasia, Duchi Roberto, Boito Simona, Barandalla Maria, Massaro Giulia, Santanatoglia Chiara, Cappellozza Enrica, Perota Andrea, Di Meo Ivano, Tiranti Valeria, Bottani Emanuela, Galli Cesare, Persico Nicola, Brunetti Dario
基因治疗
发育与干细胞
GFP
发表日期：2025
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Double transgenic neonatal porcine islets as an alternative source for beta cell replacement therapy.

双转基因新生猪胰岛作为β细胞替代疗法的替代来源

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2409138121
Mourad Nizar I, Perota Andrea, Xhema Daela, Duchi Roberto, Lagutina Irina, Galli Cesare, Gianello Pierre
细胞生物学
Porcine
发表日期：2024
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Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy

用于癌症免疫疗法的仿生糖纳米颗粒疫苗

期刊:ACS Nano
影响因子:16
doi:10.1021/acsnano.8b07241
Reuven, Eliran Moshe; Leviatan Ben-Arye, Shani; Yu, Hai; Duchi, Roberto; Perota, Andrea; Conchon, Sophie; Bachar Abramovitch, Shirley; Soulillou, Jean-Paul; Galli, Cesare; Chen, Xi; Padler-Karavani, Vered
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2019
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N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)

通过靶向 CMP-Neu5Gc 羟化酶 (CMAH) 使大型动物的 N-糖酰神经氨酸 (Neu5Gc) 基因敲除

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2019.02396
Perota, Andrea; Galli, Cesare
发表日期：2019
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Anti-EBOV GP IgGs Lacking α1-3-Galactose and Neu5Gc Prolong Survival and Decrease Blood Viral Load in EBOV-Infected Guinea Pigs

缺乏α1-3-半乳糖和Neu5Gc的抗EBOV GP IgG可延长EBOV感染豚鼠的存活期并降低其血液病毒载量

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0156775
Reynard, Olivier; Jacquot, Frédéric; Evanno, Gwénaëlle; Mai, Hoa Le; Salama, Apolline; Martinet, Bernard; Duvaux, Odile; Bach, Jean-Marie; Conchon, Sophie; Judor, Jean-Paul; Perota, Andrea; Lagutina, Irina; Duchi, Roberto; Lazzari, Giovanna; Le Berre, Ludmilla; Perreault, Hélène; Lheriteau, Elsa; Raoul, Hervé; Volchkov, Viktor; Galli, Cesare; Soulillou, Jean-Paul
炎症/感染
IgG
Guinea
微生物学
发表日期：2016
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