Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans
小分子葡萄糖激酶激活剂会扰乱啮齿动物的脂质稳态并诱发脂肪肝:这对人类的治疗应用敲响了警钟。
期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/j.1476-5381.2012.02184.x
De Ceuninck, Frédéric; Kargar, Catherine; Ilic, Catherine; Caliez, Audrey; Rolin, Jean-Olivier; Umbdenstock, Thierry; Vinson, Cédric; Combettes, Murielle; de Fanti, Brant; Harley, Elizabeth; Sadlo, Marjorie; Lefèvre, Anne-Laure; Broux, Olivier; Wierzbicki, Michel; Fourquez, Jean-Marie; Perron-Sierra, Françoise; Kotschy, András; Ktorza, Alain