日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Natural menopause, menarche and breast cancer risk in BRCA1 and BRCA2 pathogenic variant carriers: a Mendelian randomization analysis

BRCA1和BRCA2致病变异携带者的自然绝经、初潮和乳腺癌风险:一项孟德尔随机化分析

Mavaddat, Nasim; Barnes, Daniel R; Michailidou, Kyriaki; Zhao, Emily; Frost, Debra; Leslie, Goska; Dennis, Joe; Wang, Qin; Bolla, Manjeet K; Evans, D Gareth; Tischkowitz, Marc; Thompson, Deborah J; Perry, John R B; Antoniou, Antonis C; Easton, Douglas F

Higher Circulating Testosterone Linked to Higher CAD Risk in Men: Mendelian Randomization and Survival Analyses

男性体内较高的循环睾酮水平与较高的冠心病风险相关:孟德尔随机化和生存分析

Morbey, Emily J; Day, Felix R; Butterworth, Adam S; Wareham, Nicholas J; Perry, John R B; Ong, Ken K

Assessment of mosaic loss of chromosome Y in pulmonary fibrosis reveals limited association with susceptibility or disease severity

对肺纤维化中Y染色体嵌合性缺失的评估显示,其与疾病易感性或严重程度的关联有限。

Wang, Dapeng; Hadad, Niran; Moss, Samuel; Lopez-Jimenez, Elena; Johnson, Simon R; Maher, Toby M; Molyneaux, Philip L; Zhao, Yajie; Perry, John R B; Wolters, Paul J; Kropski, Jonathan A; Jenkins, R Gisli; Banovich, Nicholas E; Stewart, Iain

Author Correction: A comprehensive spatio-cellular map of the human hypothalamus

作者更正:人类下丘脑的综合空间细胞图谱

Tadross, John A; Steuernagel, Lukas; Dowsett, Georgina K C; Kentistou, Katherine A; Lundh, Sofia; Porniece, Marta; Klemm, Paul; Rainbow, Kara; Hvid, Henning; Kania, Katarzyna; Polex-Wolf, Joseph; Knudsen, Lotte Bjerre; Pyke, Charles; Perry, John R B; Lam, Brian Y H; Brüning, Jens C; Yeo, Giles S H

A comprehensive spatio-cellular map of the human hypothalamus.

人类下丘脑的综合空间细胞图谱

Tadross John A, Steuernagel Lukas, Dowsett Georgina K C, Kentistou Katherine A, Lundh Sofia, Porniece Marta, Klemm Paul, Rainbow Kara, Hvid Henning, Kania Katarzyna, Polex-Wolf Joseph, Knudsen Lotte Bjerre, Pyke Charles, Perry John R B, Lam Brian Y H, Brüning Jens C, Yeo Giles S H

Canine genome-wide association study identifies DENND1B as an obesity gene in dogs and humans

犬类全基因组关联研究发现 DENND1B 是犬类和人类的肥胖基因。

Wallis, Natalie J; McClellan, Alyce; Mörseburg, Alexander; Kentistou, Katherine A; Jamaluddin, Aqfan; Dowsett, Georgina K C; Schofield, Ellen; Morros-Nuevo, Anna; Saeed, Sadia; Lam, Brian Y H; Sumanasekera, Natasha T; Chan, Justine; Kumar, Sambhavi S; Zhang, Rey M; Wainwright, Jodie F; Dittmann, Marie; Lakatos, Gabriella; Rainbow, Kara; Withers, David; Bounds, Rebecca; Ma, Marcella; German, Alexander J; Ladlow, Jane; Sargan, David; Froguel, Philippe; Farooqi, I Sadaf; Ong, Ken K; Yeo, Giles S H; Tadross, John A; Perry, John R B; Gorvin, Caroline M; Raffan, Eleanor

Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health

基于全基因组测序的群体规模基因分析能够深入了解代谢健康。

Zhao, Yajie; Lockhart, Sam; Liu, Jimmy; Li, Xihao; Cortes, Adrian; Hua, Xing; Gardner, Eugene J; Kentistou, Katherine A; Cañadas-Garre, Marisa; Fabian, Laurie; Ho, Karen; Timpson, Nicholas; Lo, Yancy; Davitte, Jonathan; Savage, David B; Buser-Doepner, Carolyn; Ong, Ken K; Zhang, Haoyu; Scott, Robert; O'Rahilly, Stephen; Perry, John R B

Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling

罕见变异与出生体重的关联揭示了参与脂肪组织调节、胎盘功能和胰岛素样生长因子信号传导的基因。

Kentistou, Katherine A; Lim, Brandon E M; Kaisinger, Lena R; Steinthorsdottir, Valgerdur; Sharp, Luke N; Patel, Kashyap A; Tragante, Vinicius; Hawkes, Gareth; Gardner, Eugene J; Olafsdottir, Thorhildur; Wood, Andrew R; Zhao, Yajie; Thorleifsson, Gudmar; Day, Felix R; Ozanne, Susan E; Hattersley, Andrew T; O'Rahilly, Stephen; Stefansson, Kari; Ong, Ken K; Beaumont, Robin N; Perry, John R B; Freathy, Rachel M

Genetic Variants Associated With Preeclampsia and Maternal Serum sFLT1 Levels

与先兆子痫和母体血清 sFLT1 水平相关的遗传变异

Mack, Jasmine A; Sovio, Ulla; Day, Felix R; Gaccioli, Francesca; Cook, Emma; Bayzid, Nadua; Cotic, Marius; Dunton, Nathan J; Madhan, Gaganjit; Motsinger-Reif, Alison A; Perry, John R B; Charnock-Jones, D Stephen; Smith, Gordon C S

Protein-truncating variants in UQCRC1 are associated with Parkinson's disease: evidence from half-million people

UQCRC1基因中的蛋白质截短变异与帕金森病相关:来自50万人的证据

Jing, Xiaoxi; Liu, Zongzhi; Li, Wenwen; Ma, Kaiyan; Zhang, Jiaxiang; Yan, Zeqi; Zhang, Shuo; Lin, Jiecong; Zhao, Junpeng; Ong, Ken K; Perry, John R B; Zhao, Yajie