日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian cancer.

基质结构和微环境动态与卵巢癌的化疗反应相关。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2026.114858
Laforêts Florian, Kotantaki Panoraia, Elorbany Samar, Hartlebury Joseph, Joy Joash D, Malacrida Beatrice, Bryan-Ravenscroft Rachel C, Berlato Chiara, Di Federico Erica, Marshall John F, Manchanda Ranjit, Jarolimek Wolfgang, Perryman Lara, Maniati Eleni, Balkwill Frances R
卵巢癌
肿瘤
发表日期：2026
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The small molecule LOXL2 inhibitor SNT-5382 reduces cardiac fibrosis and achieves strong clinical target engagement.

小分子 LOXL2 抑制剂 SNT-5382 可减少心脏纤维化，并实现强大的临床靶点结合

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-06312-2
Perryman Lara, Findlay Alison, Baskar Jana, Charlton Brett, Foot Jonathan, Hamilton Ross, Hamprecht Dieter, Joshi Amar, Stolp Jessica, Turner Craig, Zahoor Amna, Zhou Wenbin, López Begoña, Ravassa Susana, González Arantxa, Jarolimek Wolfgang
心血管
发表日期：2025
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Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy

泛赖氨酰氧化酶抑制剂可破坏纤维炎症性肿瘤基质，使胆管癌对化疗更敏感。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000502
Burchard, Paul R; Ruffolo, Luis I; Ullman, Nicholas A; Dale, Benjamin S; Dave, Yatee A; Hilty, Bailey K; Ye, Jian; Georger, Mary; Jewell, Rachel; Miller, Christine; De Las Casas, Luis; Jarolimek, Wolfgang; Perryman, Lara; Byrne, Matthew M; Loria, Anthony; Marin, Chelsea; Chávez Villa, Mariana; Yeh, Jen Jen; Belt, Brian A; Linehan, David C; Hernandez-Alejandro, Roberto
肿瘤
炎症
肿瘤免疫
炎症/感染
胆管癌
发表日期：2024
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Retraction Note: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

撤稿声明：缺氧癌分泌组通过赖氨酰氧化酶诱导转移前骨病变

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-023-06048-x
Cox, Thomas R; Rumney, Robin M H; Schoof, Erwin M; Perryman, Lara; Høye, Anette M; Agrawal, Ankita; Bird, Demelza; Latif, Norain Ab; Forrest, Hamish; Evans, Holly R; Huggins, Iain D; Lang, Georgina; Linding, Rune; Gartland, Alison; Erler, Janine T
肿瘤
肿瘤免疫
发表日期：2023
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An activity-based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti-fibrotic therapeutic strategies

一种基于活性的生物探针能够区分新型小分子抑制剂和LOXL2抗体，并为抗纤维化治疗策略带来新的希望。

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.572
Findlay, Alison; Turner, Craig; Schilter, Heidi; Deodhar, Mandar; Zhou, Wenbin; Perryman, Lara; Foot, Jonathan; Zahoor, Amna; Yao, Yimin; Hamilton, Ross; Brock, Mary; Raso, Christina; Stolp, Jessica; Galati, Marie; Hamprecht, Dieter; Charlton, Brett; Jarolimek, Wolfgang
LOXL2
LOX
发表日期：2021
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Evaluation of the Response of Intracranial Xenografts to VEGF Signaling Inhibition Using Multiparametric MRI

利用多参数磁共振成像评估颅内异种移植对VEGF信号通路抑制的反应

期刊:Neoplasia
影响因子:7.7
doi:10.1016/j.neo.2017.05.007
Boult, Jessica K R; Box, Gary; Vinci, Maria; Perryman, Lara; Eccles, Suzanne A; Jones, Chris; Robinson, Simon P
信号转导
VEGF
EGF
发表日期：2017
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Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd-DTPA and USPIO-enhanced imaging

利用结合Gd-DTPA和USPIO增强成像的多参数MRI技术研究颅内肿瘤生长模式

期刊:NMR in Biomedicine
影响因子:2.7
doi:10.1002/nbm.3594
Boult, Jessica K R; Borri, Marco; Jury, Alexa; Popov, Sergey; Box, Gary; Perryman, Lara; Eccles, Suzanne A; Jones, Chris; Robinson, Simon P
TPA
肿瘤
肿瘤免疫
发表日期：2016
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Kinome-wide decoding of network-attacking mutations rewiring cancer signaling

全激酶组解码网络攻击突变重塑癌症信号通路

期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2015.08.056
Creixell, Pau; Schoof, Erwin M; Simpson, Craig D; Longden, James; Miller, Chad J; Lou, Hua Jane; Perryman, Lara; Cox, Thomas R; Zivanovic, Nevena; Palmeri, Antonio; Wesolowska-Andersen, Agata; Helmer-Citterich, Manuela; Ferkinghoff-Borg, Jesper; Itamochi, Hiroaki; Bodenmiller, Bernd; Erler, Janine T; Turk, Benjamin E; Linding, Rune
信号转导
肿瘤
肿瘤免疫
发表日期：2015
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Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β

通过联合靶向PDGFRα/β增强IGF1R抑制剂在儿童胶质母细胞瘤中的疗效

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-11-0205
Bielen, Aleksandra; Perryman, Lara; Box, Gary M; Valenti, Melanie; de Haven Brandon, Alexis; Martins, Vanessa; Jury, Alexa; Popov, Sergey; Gowan, Sharon; Jeay, Sebastien; Raynaud, Florence I; Hofmann, Francesco; Hargrave, Darren; Eccles, Suzanne A; Jones, Chris
IGF1
细胞生物学
发表日期：2011
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