Perthold相关文献与解析，生知库 | 链接生命科学的每一步

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

在一种新型 COVID-19 小鼠模型中，ACE2 是 SARS-CoV-2 的关键体内受体，该模型具有 TNF 和 IFNγ 驱动的免疫病理学特征。

Riem Gawish # ，Philipp Starkl # ，Lisabeth Pimenov ，Anastasiya Hladik ，Karin Lakovits ，Felicitas Oberndorfer ，Shane Jf Cronin ，Anna Ohradanova-Repic ，Gerald Wirnsberger ，Benedikt Agerer ，Lukas Endler ，Tümay Capraz ，Jan W Perthold ，Domagoj Cikes ，Rubina Koglgruber ，Astrid Hagelkruys ，Nuria Montserrat ，Ali Mirazimi ，Louis Boon ，Hannes Stockinger ，Andreas Bergthaler ，Chris Oostenbrink ，Josef M Penninger ，Sylvia Knapp

IFNγ

Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor

结构引导的 ACE2 糖基工程可提高其作为可溶性 SARS-CoV-2 诱饵受体的效力

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.73641

Tümay Capraz #, Nikolaus F Kienzl #, Elisabeth Laurent #, Jan W Perthold, Esther Föderl-Höbenreich, Clemens Grünwald-Gruber, Daniel Maresch, Vanessa Monteil, Janine Niederhöfer, Gerald Wirnsberger, Ali Mirazimi, Kurt Zatloukal, Lukas Mach, Josef M Penninger, Chris Oostenbrink, Johannes Stadlmann

Charge-Changing Perturbations and Path Sampling via Classical Molecular Dynamic Simulations of Simple Guest-Host Systems

通过经典分子动力学模拟简单客体-主体体系，研究电荷变化扰动和路径采样。

期刊:Journal of Chemical Theory and Computation

影响因子:5.5

doi:10.1021/acs.jctc.0c00719

Öhlknecht, Christoph; Perthold, Jan Walther; Lier, Bettina; Oostenbrink, Chris

发表日期：2020

文献求助收藏

An antibody with Fab-constant domains exchanged for a pair of CH3 domains

Fab 恒定结构域与一对 CH3 结构域交换的抗体

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0195442

Gordana Wozniak-Knopp, Gerhard Stadlmayr, Jan Walther Perthold, Katharina Stadlbauer, Mathias Gotsmy, Stefan Becker, Florian Rüker

信号转导

发表日期：2018

文献求助收藏

Simulation of Reversible Protein-Protein Binding and Calculation of Binding Free Energies Using Perturbed Distance Restraints

利用扰动距离约束模拟可逆蛋白质-蛋白质结合并计算结合自由能

期刊:Journal of Chemical Theory and Computation

影响因子:5.5

doi:10.1021/acs.jctc.7b00706

Perthold, Jan Walther; Oostenbrink, Chris

发表日期：2017

文献求助收藏

Recombinant Deg/HtrA proteases from Synechocystis sp. PCC 6803 differ in substrate specificity, biochemical characteristics and mechanism

来自集胞藻 PCC 6803 的重组 Deg/HtrA 蛋白酶在底物特异性、生化特性和机制方面存在差异。

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20102131

Huesgen, Pitter F; Miranda, Helder; Lam, XuanTam; Perthold, Manuela; Schuhmann, Holger; Adamska, Iwona; Funk, Christiane

发表日期：2011

文献求助收藏

Guidelines for Free-Energy Calculations Involving Charge Changes

涉及电荷变化的自由能计算指南

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

在一种新型 COVID-19 小鼠模型中，ACE2 是 SARS-CoV-2 的关键体内受体，该模型具有 TNF 和 IFNγ 驱动的免疫病理学特征。

Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor

结构引导的 ACE2 糖基工程可提高其作为可溶性 SARS-CoV-2 诱饵受体的效力

Charge-Changing Perturbations and Path Sampling via Classical Molecular Dynamic Simulations of Simple Guest-Host Systems

通过经典分子动力学模拟简单客体-主体体系，研究电荷变化扰动和路径采样。

An antibody with Fab-constant domains exchanged for a pair of CH3 domains

Fab 恒定结构域与一对 CH3 结构域交换的抗体

Simulation of Reversible Protein-Protein Binding and Calculation of Binding Free Energies Using Perturbed Distance Restraints

利用扰动距离约束模拟可逆蛋白质-蛋白质结合并计算结合自由能

Recombinant Deg/HtrA proteases from Synechocystis sp. PCC 6803 differ in substrate specificity, biochemical characteristics and mechanism

来自集胞藻 PCC 6803 的重组 Deg/HtrA 蛋白酶在底物特异性、生化特性和机制方面存在差异。