Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and hypoxia
小分子激活p53可阻断体内缺氧诱导因子1α和血管内皮生长因子的表达，并在常氧和缺氧条件下导致肿瘤细胞凋亡。
期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.00959-08
Yang, Jun; Ahmed, Afshan; Poon, Evon; Perusinghe, Nina; de Haven Brandon, Alexis; Box, Gary; Valenti, Melanie; Eccles, Suzanne; Rouschop, Kasper; Wouters, Brad; Ashcroft, Margaret
