日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clinical and Biochemical Characterization of Specific GUCY2D Alleles Associated With a Rare Form of Night Blindness

与一种罕见夜盲症相关的特定GUCY2D等位基因的临床和生化特征

Ba-Abbad, Rola; Peshenko, Igor V; Daich Varela, Malena; Lin, Siying; Arno, Gavin; Mahroo, Omar A; Egan, Catherine; Robson, Anthony G; Olshevskaya, Elena V; Dizhoor, Alexander M; Webster, Andrew R

Protein inhibitor of retinal membrane guanylyl cyclase suppresses cGMP synthesis in photoreceptors

视网膜膜鸟苷酸环化酶蛋白抑制剂抑制光感受器中cGMP的合成

Peshenko, Igor V; Olshevskaya, Elena V; Dizhoor, Alexander M

Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclase.

光感受器中磷酸二酯酶 5 的表达可以挽救膜鸟苷酸环化酶失调引起的视网膜变性

Dizhoor Alexander M, Sato Shinya, Luo Zhuokai, Tan Lyuqi, Levin Fay E, Olshevskaya Elena V, Peshenko Igor V, Kefalov Vladimir J

Safety and improved efficacy signals following gene therapy in childhood blindness caused by GUCY2D mutations

基因疗法治疗由GUCY2D突变引起的儿童失明后,安全性和疗效均有所提高

Jacobson, Samuel G; Cideciyan, Artur V; Ho, Allen C; Peshenko, Igor V; Garafalo, Alexandra V; Roman, Alejandro J; Sumaroka, Alexander; Wu, Vivian; Krishnan, Arun K; Sheplock, Rebecca; Boye, Sanford L; Cheang, Bee-Lin; Davidson, Vanessa; O'Riordan, Catherine R; Dizhoor, Alexander M; Boye, Shannon E

The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice

视网膜鸟苷酸环化酶1 (RetGC1) 中的R838S突变改变了视网膜中cGMP合成的钙敏感性,并导致转基因小鼠失明。

Dizhoor, Alexander M; Olshevskaya, Elena V; Peshenko, Igor V

Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutants

在治疗过程中,确定视网膜膜鸟苷酸环化酶 (RetGC1) 缺乏对人类 Leber 先天性黑蒙的影响:残余视锥细胞光感受器视力与突变体的生化特性相关

Jacobson, Samuel G; Cideciyan, Artur V; Peshenko, Igor V; Sumaroka, Alexander; Olshevskaya, Elena V; Cao, Lihui; Schwartz, Sharon B; Roman, Alejandro J; Olivares, Melani B; Sadigh, Sam; Yau, King-Wai; Heon, Elise; Stone, Edwin M; Dizhoor, Alexander M

Backbone (1)H, (13)C, and (15)N resonance assignments of guanylyl cyclase activating protein-1, GCAP1

鸟苷酸环化酶激活蛋白-1 (GCAP1) 的主链 (1)H、(13)C 和 (15)N 共振归属

Lim, Sunghyuk; Peshenko, Igor V; Dizhoor, Alexander M; Ames, James B

Mg2+/Ca2+ cation binding cycle of guanylyl cyclase activating proteins (GCAPs): role in regulation of photoreceptor guanylyl cyclase

鸟苷酸环化酶激活蛋白(GCAPs)的Mg2+/Ca2+阳离子结合循环:在光感受器鸟苷酸环化酶调控中的作用

Dizhoor, Alexander M; Olshevskaya, Elena V; Peshenko, Igor V

Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localization

视网膜鸟苷酸环化酶与转导蛋白α亚基的相互作用:在转导蛋白定位中的潜在作用

Rosenzweig, Derek H; Nair, K Saidas; Levay, Konstantin; Peshenko, Igor V; Crabb, John W; Dizhoor, Alexander M; Slepak, Vladlen Z