日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

NRF2 activators and the inhibitor of nuclear export, selinexor, restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1 through an NRF2-independent mechanism.

NRF2 激活剂和核输出抑制剂 selinexor 通过一种不依赖于 NRF2 的机制，靶向涉及 ACE2、TMPRSS2 和 XPO1 的网络，从而限制冠状病毒。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09724-6
Waqas Fakhar H, Silva da Costa Leandro, Zapatero-Belinchón Francisco J, Carter-Timofte Madalina E, Lasswitz Lisa, van der Horst Demi, Möller Rebecca, Dahlmann Julia, Olmer Ruth, Geffers Robert, Gerold Gisa, Olagnier David, Pessler Frank
ACE
ACE2
NRF2
发表日期：2026
文献求助 收藏

Low triglyceride levels are associated with increased risk of immune-related adverse events in patients receiving immune checkpoint inhibitors

低甘油三酯水平与接受免疫检查点抑制剂治疗的患者发生免疫相关不良事件的风险增加有关。

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2025.2547271
Möhn, Nora; Narten, Emily; Duzzi, Laura; Thomas, Janin; Grote-Levi, Lea; Beutel, Gernot; Fröhlich, Tabea; Bollmann, Benjamin-Alexander; Wirth, Thomas; von Wasielewski, Imke; Gutzmer, Ralf; Heidel, Florian; Pessler, Frank; Zobl, Walter; Schuchardt, Sven; Ivanyi, Philipp; Nay, Sandra; Skripuletz, Thomas
免疫/内分泌
发表日期：2025
文献求助 收藏

Effect of pH and buffer on substrate binding and catalysis by cis-aconitate decarboxylase.

pH 值和缓冲液对顺式乌头酸脱羧酶底物结合和催化作用的影响

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-89341-1
Zhao Mingming, Chen Chutao, Blankenfeldt Wulf, Pessler Frank, Büssow Konrad
免疫/内分泌
发表日期：2025
文献求助 收藏

Targeted metabolomic profiling reveals inflammation-associated longitudinal changes in plasma metabolites following on-pump coronary bypass surgery

靶向代谢组学分析揭示了体外循环冠状动脉旁路移植术后血浆代谢物中与炎症相关的纵向变化

期刊:Frontiers in Medicine
影响因子:3
doi:10.3389/fmed.2025.1673132
Neu, Frieder; Wacker, Max; Schuchardt, Sven; Varghese, Sam; Awad, George; Waqas, Fakhar H; Wippermann, Jens; Pessler, Frank; Veluswamy, Priya
炎症/感染
炎症
代谢
发表日期：2025
文献求助 收藏

Sex-specific DNA methylation associations with circulating urate levels and BCG-induced urate changes

性别特异性DNA甲基化与循环尿酸水平及卡介苗诱导的尿酸变化之间的关联

期刊:
影响因子:
doi:10.1038/s43856-025-01044-w
Liu, Zhaoli; Crișan, Tania O; Qi, Cancan; Gupta, Manoj Kumar; Liu, Xuan; Moorlag, Simone J C F M; Koeken, Valerie A C M; Jiang, Xun; Ballan, Mohamad; de Bree, L Charlotte J; Mourits, Vera P; Gao, Xu; Baccarelli, Andrea; Schwartz, Joel; Pessler, Frank; Guzmán, Carlos A; Li, Yang; Netea, Mihai G; Joosten, Leo A B; Xu, Cheng-Jian
表观遗传
DNA甲基化
发表日期：2025
文献求助 收藏

Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population

老年人群流感疫苗反应不佳的系统性失调和分子机制研究

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adq7006
Saumya Kumar ，Martijn Zoodsma ，Nhan Nguyen ，Rodrigo Pedroso ，Stephanie Trittel ，Peggy Riese ，Javier Botey-Bataller ，Liang Zhou ，Ahmed Alaswad ，Haroon Arshad ，Mihai G Netea ，Cheng-Jian Xu ，Frank Pessler ，Carlos A Guzmán ，Luis Graca ，Yang Li
微生物学
流感
发表日期：2024
文献求助 收藏

Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens

靶向代谢组学可识别准确的脑脊液代谢物生物标志物，用于区分伴有神经系统受累的 COVID-19 和由嗜神经病毒病原体引起的中枢神经系统感染。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-024-05422-1
Neu, Frieder; Nay, Sandra; Schuchardt, Sven; Klawonn, Frank; Skripuletz, Thomas; Suehs, Kurt-Wolfram; Pessler, Frank
炎症/感染
代谢
神经科学
微生物学
发表日期：2024
文献求助 收藏

Differential transcriptomic host responses in the early phase of viral and bacterial infections in human lung tissue explants ex vivo

离体人肺组织外植体中病毒和细菌感染早期阶段的差异性转录组宿主反应

期刊:Respiratory Research
影响因子:6.6
doi:10.1186/s12931-024-02988-8
Aaqib Sohail ,Fakhar H Waqas ,Peter Braubach ,Laurien Czichon ,Mohamed Samir ,Azeem Iqbal ,Leonardo de Araujo ,Stephan Pleschka ,Michael Steinert ,Robert Geffers ,Frank Pessler
炎症/感染
微生物学
发表日期：2024
文献求助 收藏

Vaccination Schedule and Age Influence Impaired Responsiveness to Hepatitis B Vaccination: A Randomized Trial in Central Asia

疫苗接种计划和年龄会影响乙型肝炎疫苗的免疫应答：一项在中亚进行的随机试验

期刊:Pathogens
影响因子:3.3
doi:10.3390/pathogens13121082
Heisig, Janyn; Nurmatov, Zuridin Sh; Riese, Peggy; Trittel, Stephanie; Sattarova, Gulsunai J; Temirbekova, Saikal N; Zhumagulova, Gulnara Zh; Nuridinova, Zhanylai N; Derkenbaeva, Aisuluu A; Arykbaeva, Bubuzhan K; Dzhangaziev, Bakyt I; Prokein, Jana; Klopp, Norman; Illig, Thomas; Guzmán, Carlos A; Kasymov, Omor T; Akmatov, Manas K; Pessler, Frank
肝炎
免疫/内分泌
发表日期：2024
文献求助 收藏

Sex-specific epigenetic signatures of circulating urate and its increase after BCG vaccination

循环尿酸的性别特异性表观遗传特征及其在卡介苗接种后的增加

期刊:
影响因子:
doi:10.21203/rs.3.rs-4498597/v1
Zhaoli Liu, Tania O Crișan, Cancan Qi, Manoj Kumar Gupta, Xuan Liu, Simone J C F M Moorlag, Valerie A C M Koeken, L Charlotte J de Bree, Vera P Mourits, Xu Gao, Andrea Baccarelli, Joel Schwartz, Frank Pessler, Carlos A Guzmán, Yang Li, Mihai G Netea, Leo A B Joosten, Cheng-Jian Xu
信号转导
发表日期：2024
文献求助 收藏