Peter C Doherty相关文献与解析，生知库 | 链接生命科学的每一步

Zhongfang Wang ，Lingyan Zhu ，Thi H O Nguyen ，Yanmin Wan ，Sneha Sant ，Sergio M Quiñones-Parra ，Jeremy Chase Crawford ，Auda A Eltahla ，Simone Rizzetto ，Rowena A Bull ，Chenli Qiu ，Marios Koutsakos ，E Bridie Clemens ，Liyen Loh ，Tianyue Chen ，Lu Liu ，Pengxing Cao ，Yanqin Ren ，Lukasz Kedzierski ，Tom Kotsimbos ，James M McCaw ，Nicole L La Gruta ，Stephen J Turner ，Allen C Cheng ，Fabio Luciani ，Xiaoyan Zhang ，Peter C Doherty ，Paul G Thomas ，Jianqing Xu ，Katherine Kedzierska

免疫/内分泌

T细胞

细胞生物学

Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells

揭示潜在杀手：追踪内源性流感特异性 CD8+ T 细胞

期刊:Immunology and Cell Biology

影响因子:3.2

doi:10.1111/imcb.12189

Rachael Keating, Melissa Y Morris, Wen Yue, Cory E Reynolds, Tarsha L Harris, Scott A Brown, Peter C Doherty, Paul G Thomas, Maureen A McGargill

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation

人类粘膜相关恒定 T 细胞通过 IL-18 依赖性激活促进抗病毒流感免疫

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1610750113

Liyen Loh, Zhongfang Wang, Sneha Sant, Marios Koutsakos, Sinthujan Jegaskanda, Alexandra J Corbett, Ligong Liu, David P Fairlie, Jane Crowe, Jamie Rossjohn, Jianqing Xu, Peter C Doherty, James McCluskey, Katherine Kedzierska

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

针对流感病毒的通用 HLA-A*0201 限制性 CD8+ T 细胞免疫的分子基础

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1603106113

Sophie A Valkenburg, Tracy M Josephs, E Bridie Clemens, Emma J Grant, Thi H O Nguyen, George C Wang, David A Price, Adrian Miller, Steven Y C Tong, Paul G Thomas, Peter C Doherty, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8⁺ T cells

从重症H7N9疾病中康复与多种免疫应答机制相关，其中以CD8⁺ T细胞为主。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms7833

Zhongfang Wang ，Yanmin Wan ，Chenli Qiu ，Sergio Quiñones-Parra ，Zhaoqin Zhu ，Liyen Loh ，Di Tian ，Yanqin Ren ，Yunwen Hu ，Xiaoyan Zhang ，Paul G Thomas ，Michael Inouye ，Peter C Doherty ，Katherine Kedzierska ，Jianqing Xu

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

灭活流感疫苗可提供快速、先天免疫系统介导的保护以及随后的长期适应性免疫

期刊:mBio

影响因子:5.1

doi:10.1128/mBio.01024-15

Brendon Y Chua, Chinn Yi Wong, Edin J Mifsud, Kathryn M Edenborough, Toshiki Sekiya, Amabel C L Tan, Francesca Mercuri, Steve Rockman, Weisan Chen, Stephen J Turner, Peter C Doherty, Anne Kelso, Lorena E Brown, David C Jackson

Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR α- and β-chain diversity in the face of peptide-MHC class I specificity

单一流感病毒特异性 TCR 链的固定表达表明，在肽-MHC I 类特异性面前，TCR α 链和 β 链具有多样性

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1401792

E Bridie Clemens, Peter C Doherty, Nicole L La Gruta, Stephen J Turner

Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells

高度病理性甲型流感病毒感染与功能受损的病毒特异性 CD8+ T 细胞增强 PD-1 表达有关

期刊:Journal of Virology

影响因子:4

doi:10.1128/JVI.02851-13

John A Rutigliano, Shalini Sharma, Melissa Y Morris, Thomas H Oguin 3rd, Jennifer L McClaren, Peter C Doherty, Paul G Thomas

Helping themselves: optimal virus-specific CD4 T cell responses require help via CD4 T cell licensing of dendritic cells

自救：最佳病毒特异性 CD4 T 细胞反应需要通过 CD4 T 细胞许可树突状细胞来实现

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1303359

Matthew R Olson, Shirley G K Seah, Jolie Cullen, Marie Greyer, Kathryn Edenborough, Peter C Doherty, Sammy Bedoui, Andrew M Lew, Stephen J Turner

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus

激酶 mTOR 调节抗体反应，为致命的流感病毒感染提供交叉保护性免疫

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/ni.2741

Rachael Keating, Tomer Hertz, Marie Wehenkel, Tarsha L Harris, Benjamin A Edwards, Jennifer L McClaren, Scott A Brown, Sherri Surman, Zachary S Wilson, Philip Bradley, Julia Hurwitz, Hongbo Chi, Peter C Doherty, Paul G Thomas, Maureen A McGargill

Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease

在致命的H7N9疾病期间，克隆多样性的CD38+HLA-DR+CD8+ T细胞持续存在。

Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells

揭示潜在杀手：追踪内源性流感特异性 CD8+ T 细胞

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation

人类粘膜相关恒定 T 细胞通过 IL-18 依赖性激活促进抗病毒流感免疫

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

针对流感病毒的通用 HLA-A*0201 限制性 CD8+ T 细胞免疫的分子基础

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8⁺ T cells

从重症H7N9疾病中康复与多种免疫应答机制相关，其中以CD8⁺ T细胞为主。

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity

灭活流感疫苗可提供快速、先天免疫系统介导的保护以及随后的长期适应性免疫

Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR α- and β-chain diversity in the face of peptide-MHC class I specificity

单一流感病毒特异性 TCR 链的固定表达表明，在肽-MHC I 类特异性面前，TCR α 链和 β 链具有多样性

Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells

高度病理性甲型流感病毒感染与功能受损的病毒特异性 CD8+ T 细胞增强 PD-1 表达有关

Helping themselves: optimal virus-specific CD4 T cell responses require help via CD4 T cell licensing of dendritic cells

自救：最佳病毒特异性 CD4 T 细胞反应需要通过 CD4 T 细胞许可树突状细胞来实现

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus

激酶 mTOR 调节抗体反应，为致命的流感病毒感染提供交叉保护性免疫