Peter M Clark相关文献与解析，生知库 | 链接生命科学的每一步

Early Reduction of Glucose Consumption Is a Biomarker of Kinase Inhibitor Efficacy Which Can Be Reversed with GLUT1 Overexpression in Lung Cancer Cells

早期葡萄糖消耗减少是激酶抑制剂疗效的生物标志物，可通过肺癌细胞中的 GLUT1 过表达来逆转

期刊:Molecular Imaging and Biology

影响因子:3

doi:10.1007/s11307-022-01782-6

Chiara Ghezzi, Stefani Perez #, Kaitlin Ryan #, Alicia Wong, Bao Ying Chen, Robert Damoiseaux, Peter M Clark

ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

ITR-Seq 是一种新一代测序检测方法，可在腺相关病毒载体介导的基因组编辑后在体内识别全基因组 DNA 编辑位点

期刊:BMC Genomics

影响因子:3.5

doi:10.1186/s12864-020-6655-4

Camilo Breton, Peter M Clark, Lili Wang, Jenny A Greig, James M Wilson

A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes

基因定义的疾病模型揭示尿路上皮细胞可以引发不同的膀胱癌表型

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1915770117

Liang Wang, Bryan A Smith, Nikolas G Balanis, Brandon L Tsai, Kim Nguyen, Michael W Cheng, Matthew B Obusan, Favour N Esedebe, Saahil J Patel, Hanwei Zhang, Peter M Clark, Anthony E Sisk, Jonathan W Said, Jiaoti Huang, Thomas G Graeber, Owen N Witte, Arnold I Chin, Jung Wook Park

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells

高通量筛选确定 CDK7 激活肺癌细胞中的葡萄糖消耗

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-019-13334-8

Chiara Ghezzi, Alicia Wong, Bao Ying Chen, Bernard Ribalet, Robert Damoiseaux, Peter M Clark

The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier

GPI锚定蛋白LY6A驱动AAV-PHP.B跨越血脑屏障

期刊:Molecular Therapy

影响因子:12.1

doi:10.1016/j.ymthe.2019.02.013

Juliette Hordeaux ,Yuan Yuan ,Peter M Clark ,Qiang Wang ,R Alexander Martino ,Joshua J Sims ,Peter Bell ,Angela Raymond ,William L Stanford ,James M Wilson

Noninvasive Imaging of Drug-Induced Liver Injury with 18F-DFA PET

使用 18F-DFA PET 对药物性肝损伤进行无创成像

期刊:Journal of Nuclear Medicine

影响因子:9.1

doi:10.2967/jnumed.117.206961

Jessica R Salas, Bao Ying Chen, Alicia Wong, Sergio Duarte, Stephanie A K Angarita, Gerald S Lipshutz, Owen N Witte, Peter M Clark

肝损伤

发表日期：2018

文献求助收藏

18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis

18F-FAC PET 选择性成像自身免疫性肝炎小鼠模型中的肝浸润 CD4 和 CD8 T 细胞

期刊:Journal of Nuclear Medicine

影响因子:9.1

doi:10.2967/jnumed.118.210328

Jessica R Salas, Bao Ying Chen, Alicia Wong, Donghui Cheng, John S Van Arnam, Owen N Witte, Peter M Clark

Pretest Measures of the Study Outcome and the Elimination of Selection Bias: Evidence from Three Within Study Comparisons

研究结果的预测试指标及选择偏倚的消除：来自三项研究内比较的证据

期刊:Prevention Science

影响因子:2.7

doi:10.1007/s11121-016-0732-6

Hallberg, Kelly; Cook, Thomas D; Steiner, Peter M; Clark, M H

发表日期：2018

文献求助收藏

Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma

细胞质 p53 将致癌基因驱动的葡萄糖代谢与细胞凋亡联系起来，是胶质母细胞瘤的治疗靶点

期刊:Nature Medicine

影响因子:58.7

doi:10.1038/nm.4418

Wilson X Mai, Laura Gosa, Veerle W Daniels, Lisa Ta, Jonathan E Tsang, Brian Higgins, W Blake Gilmore, Nicholas A Bayley, Mitra Dehghan Harati, Jason T Lee, William H Yong, Harley I Kornblum, Steven J Bensinger, Paul S Mischel, P Nagesh Rao, Peter M Clark, Timothy F Cloughesy, Anthony Letai, David A

Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3

Pacritinib 通过靶向 FLT3 抑制鳞状细胞肺癌细胞的葡萄糖消耗

Early Reduction of Glucose Consumption Is a Biomarker of Kinase Inhibitor Efficacy Which Can Be Reversed with GLUT1 Overexpression in Lung Cancer Cells

早期葡萄糖消耗减少是激酶抑制剂疗效的生物标志物，可通过肺癌细胞中的 GLUT1 过表达来逆转

ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

ITR-Seq 是一种新一代测序检测方法，可在腺相关病毒载体介导的基因组编辑后在体内识别全基因组 DNA 编辑位点

A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes

基因定义的疾病模型揭示尿路上皮细胞可以引发不同的膀胱癌表型

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells

高通量筛选确定 CDK7 激活肺癌细胞中的葡萄糖消耗

The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier

GPI锚定蛋白LY6A驱动AAV-PHP.B跨越血脑屏障

Noninvasive Imaging of Drug-Induced Liver Injury with 18F-DFA PET

使用 18F-DFA PET 对药物性肝损伤进行无创成像

18F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis

18F-FAC PET 选择性成像自身免疫性肝炎小鼠模型中的肝浸润 CD4 和 CD8 T 细胞

Pretest Measures of the Study Outcome and the Elimination of Selection Bias: Evidence from Three Within Study Comparisons

研究结果的预测试指标及选择偏倚的消除：来自三项研究内比较的证据

Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma

细胞质 p53 将致癌基因驱动的葡萄糖代谢与细胞凋亡联系起来，是胶质母细胞瘤的治疗靶点