日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Modi-2 a vaccine stimulating CD4 responses to homocitrullinated self epitopes as therapy for solid cancers

Modi-2 是一种刺激 CD4 对同型瓜氨酸化自身表位反应的疫苗，可用于治疗实体癌

期刊:NPJ Vaccines
影响因子:6.9
doi:10.1038/s41541-024-01029-1
Abdullah A Al-Omari, Katherine W Cook, Peter Symonds, Anne Skinner, Alissa Wright, Yaling Zhu, Vincent L Coble, Omar J Mohammed, Ruhul H Choudhury, Nazim Uddin, Priscilla Ranglani, Adrian Parry, Sally E Adams, Geoffrey M Lynn, Lindy G Durrant, Victoria A Brentville
肿瘤
发表日期：2024
文献求助 收藏

Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity

接种翻译后修饰的同型瓜氨酸化肽可诱导介导抗肿瘤免疫的 CD8 T 细胞反应

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2023-006966
Sabaria Shah, Katherine W Cook, Peter Symonds, Juliane Weißer, Anne Skinner, Abdullah Al Omari, Samantha J Paston, Ian Pike, Lindy G Durrant, Victoria A Brentville
信号转导
肿瘤
T细胞
Translational Control
发表日期：2023
文献求助 收藏

FIT for purpose: study protocol for a randomized controlled trial to personalize surveillance colonoscopy for individuals at elevated risk of colorectal cancer

FIT for purpose：一项随机对照试验的研究方案，旨在为结直肠癌高风险人群制定个性化的监测性结肠镜检查方案

期刊:International Journal of Colorectal Disease
影响因子:2.3
doi:10.1007/s00384-023-04493-8
Winter, Jean M; Cornthwaite, Kathryn J; Young, Graeme P; Wilson, Carlene; Chen, Gang; Woodman, Richard; Coats, Michelle; Fraser, Robert; Cock, Charles; Bampton, Peter; Symonds, Erin L
肿瘤
肠癌
肿瘤免疫
发表日期：2023
文献求助 收藏

PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

PAD-2介导的核磷蛋白瓜氨酸化为肿瘤免疫治疗提供了有效的靶点

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2021-003526
Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant
信号转导
肿瘤
Cell Depletion
WB
Mouse
CD8A
发表日期：2022
文献求助 收藏

Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

疫苗可通过多种 HLA 类型诱导 CD4 介导的对同型瓜氨酸肽的反应并产生抗肿瘤免疫力

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2022.873947
Katherine Cook, Wei Xue, Suha Atabani, Peter Symonds, Abdullah Al Omari, Ian Daniels, Sabaria Shah, Ruhul Hasan Choudhury, Daisy Weston, Rachael Metheringham, Victoria Brentville, Lindy Durrant
免疫
肿瘤
发表日期：2022
文献求助 收藏

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy

瓜氨酸化葡萄糖调节蛋白 78 是黑色素瘤免疫治疗的候选靶点

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2022.1066185
Victoria Anne Brentville, Peter Symonds, JiaXin Chua, Anne Skinner, Ian Daniels, Katherine Wendy Cook, Sasa Koncarevic, Roxana Martinez-Pinna, Sabaria Shah, Ruhul Hasan Choudhury, Poonam Vaghela, Daisy Weston, Abdullah Al-Omari, James Davis, Lindy G Durrant
免疫
黑色素瘤
发表日期：2022
文献求助 收藏

Citrullinated Epitopes Identified on Tumour MHC Class II by Peptide Elution Stimulate Both Regulatory and Th1 Responses and Require Careful Selection for Optimal Anti-Tumour Responses

通过肽洗脱鉴定的肿瘤 MHC II 类上的瓜氨酸化表位可刺激调节和 Th1 反应，需要仔细选择才能获得最佳抗肿瘤反应

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2021.764462
Peter Symonds, Ana Marcu, Katherine W Cook, Rachael L Metheringham, Lindy G Durrant, Victoria A Brentville
肿瘤
发表日期：2021
文献求助 收藏

T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumour therapy

健康人体内对瓜氨酸化自身肽的 T 细胞库并不局限于 HLA-DR SE 等位基因；针对 HLA-DP4 呈递的瓜氨酸化自身肽进行肿瘤治疗

期刊:Oncoimmunology
影响因子:
doi:10.1080/2162402X.2019.1576490
Victoria A Brentville, Peter Symonds, Katherine W Cook, Ian Daniels, Tracy Pitt, Mohamed Gijon, Poonam Vaghela, Wei Xue, Sabaria Shah, Rachael L Metheringham, Lindy G Durrant
肿瘤
T细胞
Human
发表日期：2019
文献求助 收藏

Citrullinated α-enolase is an effective target for anti-cancer immunity

瓜氨酸化α-烯醇化酶是抗癌免疫的有效靶点

期刊:Oncoimmunology
影响因子:
doi:10.1080/2162402X.2017.1390642
Katherine Cook, Ian Daniels, Peter Symonds, Tracy Pitt, Mohamed Gijon, Wei Xue, Rachael Metheringham, Lindy Durrant, Victoria Brentville
肿瘤
发表日期：2017
文献求助 收藏

Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell-Mediated Antitumor Immunity

肿瘤细胞中 MHC-II 上呈递的瓜氨酸化波形蛋白是 CD4+ T 细胞介导的抗肿瘤免疫的靶点

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-15-1085
Victoria A Brentville, Rachael L Metheringham, Barbara Gunn, Peter Symonds, Ian Daniels, Mohamed Gijon, Katherine Cook, Wei Xue, Lindy G Durrant
信号转导
肿瘤
T细胞
发表日期：2016
文献求助 收藏