日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Smooth-to-rough morphotype switching, a mechanism of phage resistance in Mycobacterium abscessus

脓肿分枝杆菌噬菌体抗性的光滑型到粗糙型形态转换

Liew, Jun Hao; Norman, Ayuni; Illouz, Morgane; Teo, Teck-Hui; Ponti, Riccardo Delli; Hamela, Claire; Mohan, Lalit; Lew, Renee; Ron, Chanvutha; Low, Kay En; Daher, Wassim; Chiam, Aryeh; Maw, Joanna; Sun, Yan; Sorayah, Ria; Oehlers, Stefan H; Jhun, Byung Woo; Teo, Jeanette W P; Goulet, Adeline; Bonne, Isabelle; Wintjens, René; Pethe, Kevin; Huber, Roland G; Kremer, Laurent; Bifani, Pablo

A bactericidal tuberculosis drug regimen driven by inhibition of the terminal oxidases by pretomanid.

普瑞托马尼通过抑制末端氧化酶发挥杀菌结核病药物治疗作用。

Rahman Nurlilah Ab, Singh Samsher, Wiggins Thomas, Santos May Delos, Moraski Garrett C, Miller Marvin J, Berney Michael, Pethe Kevin

A Series of Pyrazolo-Quinazoline Amines Inhibits the Cytochrome bd Oxidase in Mycobacterium tuberculosis

一系列吡唑并喹唑啉胺类化合物抑制结核分枝杆菌中的细胞色素bd氧化酶

Singh, Samsher; Ng, Pearly Shuyi; Lakshmanan, Umayal; Mathiyazakan, Vikneswaran; Wiggins, Thomas; Lee, Bei Shi; Ang, Shi Hua; Lin Sim, Sandra Wei; Santos, May Delos; Moraski, Garrett; Miller, Marvin; Berney, Michael; Grüber, Gerhard; Pethe, Kevin

Gelatinase regulates the egress of intracellular replicating populations during Enterococcus faecalis infection.

明胶酶在粪肠球菌感染过程中调节细胞内复制菌群的逸出。

Tanoto Frederick Reinhart, Liew Jia Hui, Stocks Claudia J, Rawat Deepti, Chong Kelvin Kian Long, Pethe Kevin, Antypas Haris, Kline Kimberly A

Carbene formation as a mechanism for efficient intracellular uptake of cationic antimicrobial carbon acid polymers

卡宾的形成是阳离子抗菌碳酸聚合物高效胞内吸收的机制

Koh, Chong Hui; Lambu, Mallikharjuna Rao; Tan, Chongyun; Wei, Guangmin; Kok, Zhi Yuan; Zhang, Kaixi; Vu, Quang Huy Nhat; Panneerselvam, Muthuvel; Ooi, Ying Jie; Tan, Shiow Han; Wang, Zheng; Tatina, Madhu Babu; Ng, Justin Tze Yang; Guo, Aoxin; Tonanon, Panyawut; Dang, Tram T; Gan, Yunn-Hwen; Mu, Yuguang; Hammond, Paula T; Chi, Yonggui Robin; Webster, Richard D; Pullarkat, Sumod A; Li, Qingjie; Greenberg, E Peter; Gründling, Angelika; Pethe, Kevin; Chan-Park, Mary B

Unprecedented in vivo activity of telacebec against Mycobacterium leprae

telacebec 对麻风分枝杆菌具有前所未有的体内活性

Chauffour, Aurélie; Cambau, Emmanuelle; Pethe, Kevin; Veziris, Nicolas; Aubry, Alexandra

The mycobacterial ATP burst is a lysis artifact and serves as an assay for drug-induced cell wall damage

分枝杆菌ATP爆发是裂解过程中产生的假象,可作为药物诱导细胞壁损伤的检测方法。

Mulholland, Claire V; Lee, Bei Shi; Chong, Alexander; Cui, Jinhua; Pethe, Kevin; Berney, Michael

A bioluminescence-based chemical screen identifies a bactericidal naphthalene scaffold targeting MmpL3 in Mycobacterium abscessus

基于生物发光的化学筛选鉴定出一种靶向脓肿分枝杆菌中 MmpL3 的杀菌萘骨架

Singh, Samsher; Sorayah, Ria; Chen, Yushu; Mulholland, Claire V; Daher, Wassim; Pee, Carmen J E; Casandra, Tan Ai Zhu; Wee, Denise; Oehlers, Stefan H; Kline, Kimberly A; Chng, Shu Sin; Berney, Michael; Kremer, Laurent; Moraski, Garrett; Pethe, Kevin

An optimized cyclophosphamide-treated mouse model of Mycobacterium abscessus pulmonary infection

一种优化的环磷酰胺治疗的脓肿分枝杆菌肺部感染小鼠模型

Sun, Yan; Zhang, Kaixi; Delos Santos, May; Pee, Carmen J E; Yang, Yanmeng; Kang, Meiqi; Shin, Sung Jae; Chan-Park, Mary B; Pethe, Kevin

High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo

F-ATP合酶抑制剂TBAJ-5307在体外和体内对非结核分枝杆菌均具有高效性

Ragunathan, Priya; Sae-Lao, Patcharaporn; Hamela, Claire; Alcaraz, Matthéo; Krah, Alexander; Poh, Wee Han; Ern Pee, Carmen Jia; Hou Lim, Albert Yick; Rice, Scott A; Pethe, Kevin; Bond, Peter J; Dick, Thomas; Kremer, Laurent; Bates, Roderick W; Grüber, Gerhard