日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors

利用 CombiCells(一种用于细胞表面配体滴定和组合展示的平台)研究辅助受体对 T 细胞抗原敏感性的调节

Ashna Patel ,Violaine Andre ,Sofia Bustamante Eguiguren ,Michael I Barton ,Jake Burton ,Eleanor M Denham ,Johannes Pettmann ,Alexander M Mørch ,Mikhail A Kutuzov ,Jesús A Siller-Farfán ,Michael L Dustin ,P Anton van der Merwe ,Omer Dushek

Mechanical forces impair antigen discrimination by reducing differences in T-cell receptor/peptide-MHC off-rates

机械力通过减少 T 细胞受体/肽-MHC 解离率的差异来削弱抗原识别

Johannes Pettmann #, Lama Awada #, Bartosz Różycki, Anna Huhn, Sara Faour, Mikhail Kutuzov, Laurent Limozin, Thomas R Weikl, P Anton van der Merwe, Philippe Robert #, Omer Dushek #

Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors

辅助受体利用不充分会降低嵌合抗原受体的敏感性

Jake Burton, Jesús A Siller-Farfán, Johannes Pettmann, Benjamin Salzer, Mikhail Kutuzov, P Anton van der Merwe, Omer Dushek

T cell microvilli simulations show operation near packing limit and impact on antigen recognition

T细胞微绒毛模拟显示,其在接近堆积极限时发挥作用,并影响抗原识别。

Morgan, Jonathan; Pettmann, Johannes; Dushek, Omer; Lindsay, Alan E

Quantitative contributions of TNF receptor superfamily members to CD8+ T-cell responses

TNF受体超家族成员对CD8+ T细胞反应的定量贡献

John Nguyen,Johannes Pettmann,Philipp Kruger,Omer Dushek

The discriminatory power of the T cell receptor

T细胞受体的鉴别能力

Johannes Pettmann # ,Anna Huhn # ,Enas Abu Shah # ,Mikhail A Kutuzov ,Daniel B Wilson ,Michael L Dustin ,Simon J Davis ,P Anton van der Merwe ,Omer Dushek

Perfect adaptation of CD8+ T cell responses to constant antigen input over a wide range of affinities is overcome by costimulation

CD8+ T 细胞对各种亲和力的恒定抗原输入的完美适应性反应被共刺激所克服

Nicola Trendel, Philipp Kruger, Stephanie Gaglione, John Nguyen, Johannes Pettmann, Eduardo D Sontag, Omer Dushek

Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses

人类 CD8+ T 细胞对不同的效应反应表现出共同的抗原阈值

Enas Abu-Shah, Nicola Trendel, Philipp Kruger, John Nguyen, Johannes Pettmann, Mikhail Kutuzov, Omer Dushek

Membrane Ultrastructure and T Cell Activation

膜超微结构与T细胞活化

Pettmann, Johannes; Santos, Ana Mafalda; Dushek, Omer; Davis, Simon J

Death Receptors in the Selective Degeneration of Motoneurons in Amyotrophic Lateral Sclerosis

肌萎缩侧索硬化症中运动神经元选择性退化中的死亡受体

Aebischer, Julianne; Bernard-Marissal, Nathalie; Pettmann, Brigitte; Raoul, Cédric