日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium.

神经创伤引起的视网膜基底膜 COL4A1 缺陷可通过脂肪组织来源的间充质干细胞浓缩条件培养基进行修复。

Rasiah Pratheepa Kumari, Jha Kumar Abhiram, Gentry Jordy, Del Mar Nobel A, Pfeffer Lawrence M, Reiner Anton, Gangaraju Rajashekhar

Structural Activity Relationship Analysis of New Diphenyl PFI-3 Analogues Targeting for the Treatment of Glioblastoma

针对胶质母细胞瘤治疗的新型二苯基PFI-3类似物的结构活性关系分析

Hwang, Dong-Jin; Yang, Chuanhe; Wang, Yinan; Kelso, Hannah; Pochampally, Satyanarayana; Pfeffer, Lawrence M; Miller, Duane D

A Pyrimidine-Based Tubulin Inhibitor Shows Potent Anti-Glioblastoma Activity In Vitro and In Vivo

一种基于嘧啶的微管蛋白抑制剂在体外和体内均显示出强大的抗胶质母细胞瘤活性

Pochampally, Satyanarayana; Pfeffer, Lawrence M; Miranda-Carboni, Gustavo A; Daniel, Macey; James, Jazz I; Smith, Allana; Yang, Chuan He; Kelso, Hannah R; Parke, Deanna N; Hwang, Dong-Jin; Li, Wei; Miller, Duane D

Tyr1497 in the BRG1 Bromodomain of the SWI/SNF Complex is Critical for the Binding and Function of a Selective BRG1 Inhibitor

SWI/SNF复合物BRG1溴结构域中的Tyr1497对于选择性BRG1抑制剂的结合和功能至关重要

Wang, Yinan; Yang, Chuanhe; Miranda-Carboni, Gustavo A; Kelso, Hannah; Seetharaman, Jayaraman; Hwang, Dong-Jin; Miller, Duane D; Pfeffer, Lawrence M

Comprehensive molecular analysis of uveal melanoma identifies targets in tumor-intrinsic and tumor-extrinsic pathways.

对葡萄膜黑色素瘤进行全面的分子分析,确定肿瘤内在和肿瘤外在通路中的靶点。

Cernichiaro-Espinosa Linda A, Miranda-Carboni Gustavo A, Taylor-Gonzalez David J, Choi Sue, Cruz Anthony, Musicante Robert, Cox Braden, Allen-Winters Stephanie, Wang Yinan, Yang Chuan He, Morales-Tirado Vanessa, Pfeffer Lawrence M, Wilson Matthew W

MiR-675 Inhibits Primary Ovarian Tumor Growth and Metastasis by Suppressing EMT and TGFβ Signaling

miR-675通过抑制EMT和TGFβ信号通路抑制原发性卵巢肿瘤的生长和转移

Zhao, Xinxin; Liu, Ziping; Li, Yongshuai; Song, Shiji; Wang, Baojin; Pfeffer, Lawrence M; Zhang, Wenjing; Yue, Junming

A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity

ER阳性乳腺癌中肿瘤抑制基因向癌基因的分子转换:雄激素受体、JAK-STAT和谱系可塑性的作用

Asemota, Sarah; Effah, Wendy; Holt, Jeremiah; Johnson, Daniel; Cripe, Linnea; Ponnusamy, Suriyan; Thiyagarajan, Thirumagal; Khosrosereshki, Yekta; Hwang, Dong-Jin; He, Yali; Grimes, Brandy; Fleming, Martin D; Pritchard, Frances E; Hendrix, Ashley; Fan, Meiyun; Jain, Abhinav; Choi, Hyo Young; Makowski, Liza; Hayes, D Neil; Miller, Duane D; Pfeffer, Lawrence M; Santhanam, Balaji; Narayanan, Ramesh

Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer

利用半胱氨酸选择性不可逆共价抑制剂抑制雄激素受体剪接变体来治疗前列腺癌

Thiyagarajan, Thirumagal; Ponnusamy, Suriyan; Hwang, Dong-Jin; He, Yali; Asemota, Sarah; Young, Kirsten L; Johnson, Daniel L; Bocharova, Vera; Zhou, Weidong; Jain, Abhinav K; Petricoin, Emanuel F; Yin, Zheng; Pfeffer, Lawrence M; Miller, Duane D; Narayanan, Ramesh

The STAT3-Regulated Autophagy Pathway in Glioblastoma

胶质母细胞瘤中STAT3调控的自噬通路

Laribee, Ronald Nicholas; Boucher, Andrew B; Madireddy, Saivikram; Pfeffer, Lawrence M

Next-generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma

新一代SWI/SNF复合物溴结构域抑制剂可增强胶质母细胞瘤中的DNA损伤和细胞死亡

Yang, Chuanhe; He, Yali; Wang, Yinan; McKinnon, Peter J; Shahani, Vijay; Miller, Duane D; Pfeffer, Lawrence M