日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.

自噬通过 SQSTM1/p62 介导的选择性自噬来调节细胞衰老,从而介导 CDKN1A/p21 和 CDKN2A/p16 的降解,进而导致粘液瘤样二尖瓣退化

Tang Qiyu, Tang Keyi, Markby Greg R, Parys Maciej, Phadwal Kanchan, MacRae Vicky E, Corcoran Brendan M

The Role of Transforming Growth Factor-β Signaling in Myxomatous Mitral Valve Degeneration

转化生长因子-β信号通路在黏液瘤样二尖瓣退行性变中的作用

Tang, Qiyu; McNair, Andrew J; Phadwal, Kanchan; Macrae, Vicky E; Corcoran, Brendan M

Mitochondrial Dysfunction: Cause or Consequence of Vascular Calcification?

线粒体功能障碍:血管钙化的原因还是结果?

Phadwal, Kanchan; Vrahnas, Christina; Ganley, Ian G; MacRae, Vicky E

Osteoblast-specific deficiency of ectonucleotide pyrophosphatase or phosphodiesterase-1 engenders insulin resistance in high-fat diet fed mice

成骨细胞特异性缺乏外核苷酸焦磷酸酶或磷酸二酯酶-1会导致高脂饮食喂养的小鼠出现胰岛素抵抗。

Roberts, Fiona L; Rashdan, Nabil A; Phadwal, Kanchan; Markby, Greg R; Dillon, Scott; Zoll, Janna; Berger, Julian; Milne, Elspeth; Orriss, Isabel R; Karsenty, Gerard; Le Saux, Olivier; Morton, Nicholas M; Farquharson, Colin; MacRae, Vicky E

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations

OPA1基因突变引起的视神经萎缩中线粒体自噬和线粒体组织失调

Liao, Chunyan; Ashley, Neil; Diot, Alan; Morten, Karl; Phadwal, Kanchan; Williams, Andrew; Fearnley, Ian; Rosser, Lyndon; Lowndes, Jo; Fratter, Carl; Ferguson, David J P; Vay, Laura; Quaghebeur, Gerardine; Moroni, Isabella; Bianchi, Stefania; Lamperti, Costanza; Downes, Susan M; Sitarz, Kamil S; Flannery, Padraig J; Carver, Janet; Dombi, Eszter; East, Daniel; Laura, Matilde; Reilly, Mary M; Mortiboys, Heather; Prevo, Remko; Campanella, Michelangelo; Daniels, Matthew J; Zeviani, Massimo; Yu-Wai-Man, Patrick; Simon, Anna Katharina; Votruba, Marcela; Poulton, Joanna

Autophagy Controls Acquisition of Aging Features in Macrophages

自噬控制巨噬细胞衰老特征的获得

Stranks, Amanda J; Hansen, Anne Louise; Panse, Isabel; Mortensen, Monika; Ferguson, David J P; Puleston, Daniel J; Shenderov, Kevin; Watson, Alexander Scarth; Veldhoen, Marc; Phadwal, Kanchan; Cerundolo, Vincenzo; Simon, Anna Katharina

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging

走钢丝:自噬在干细胞更新、分化、增殖和衰老中的作用

Phadwal, Kanchan; Watson, Alexander Scarth; Simon, Anna Katharina

T-cell epitope prediction and immune complex simulation using molecular dynamics: state of the art and persisting challenges

利用分子动力学进行T细胞表位预测和免疫复合物模拟:现状与挑战

Flower, Darren R; Phadwal, Kanchan; Macdonald, Isabel K; Coveney, Peter V; Davies, Matthew N; Wan, Shunzhou