日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SARS-CoV-2 Mpro inhibitor ensitrelvir: asymmetrical cross-resistance with nirmatrelvir and emerging resistance hotspots

SARS-CoV-2 Mpro抑制剂恩西替利韦:与尼尔马替利韦存在不对称交叉耐药性及耐药性热点地区出现

Zhou, Yuyong; Gammeltoft, Karen A; Tjørnelund-Sjursen, Helena D; Ryberg, Line A; Offersgaard, Anna; Czarnota, Anna; Duan, Zhe; Pham, Long V; Fahnøe, Ulrik; Peters, Günther H J; Ramirez, Santseharay; Bukh, Jens; Gottwein, Judith M

SARS-CoV-2 Remdesivir Exposure Leads to Different Evolutionary Pathways That Converge in Moderate Levels of Drug Resistance.

SARS-CoV-2 暴露于瑞德西韦会导致不同的进化路径,最终汇聚成中等程度的耐药性

Fernandez-Antunez Carlota, Ryberg Line A, Wang Kuan, Pham Long V, Mikkelsen Lotte S, Fahnøe Ulrik, Hartmann Katrine T, Jensen Henrik E, Holmbeck Kenn, Bukh Jens, Ramirez Santseharay

Neutralisation resistance of SARS-CoV-2 spike-variants is primarily mediated by synergistic receptor binding domain substitutions.

SARS-CoV-2 刺突蛋白变种的抗中和作用主要由受体结合域的协同替换介导

Pham Long V, Underwood Alexander P, Binderup Alekxander, Fahnøe Ulrik, Fernandez-Antunez Carlota, Lopez-Mendez Blanca, Ryberg Line Abildgaard, Galli Andrea, Sølund Christina, Weis Nina, Ramirez Santseharay, Bukh Jens

Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication.

用于研究抗病毒耐药性和复制的多功能 SARS-CoV-2 反向遗传学系统

Fahnøe Ulrik, Pham Long V, Fernandez-Antunez Carlota, Costa Rui, Rivera-Rangel Lizandro René, Galli Andrea, Feng Shan, Mikkelsen Lotte S, Gottwein Judith M, Scheel Troels K H, Ramirez Santseharay, Bukh Jens

Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants

高适应性和耐药性丙型肝炎病毒蛋白酶抑制剂逃逸变异株持续存在的进化途径

Jensen, Sanne Brun; Fahnøe, Ulrik; Pham, Long V; Serre, Stéphanie Brigitte Nelly; Tang, Qi; Ghanem, Lubna; Pedersen, Martin Schou; Ramirez, Santseharay; Humes, Daryl; Pihl, Anne Finne; Filskov, Jonathan; Sølund, Christina Søhoel; Dietz, Julia; Fourati, Slim; Pawlotsky, Jean-Michel; Sarrazin, Christoph; Weis, Nina; Schønning, Kristian; Krarup, Henrik; Bukh, Jens; Gottwein, Judith Margarete

Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors

高效的丙型肝炎病毒1b型核心-NS5A重组体可用于蛋白酶和NS5A抑制剂的疗效测试

Pham, Long V; Ramirez, Santseharay; Carlsen, Thomas H R; Li, Yi-Ping; Gottwein, Judith M; Bukh, Jens

Stearoyl coenzyme A desaturase 1 is associated with hepatitis C virus replication complex and regulates viral replication

硬脂酰辅酶A去饱和酶1与丙型肝炎病毒复制复合物相关,并调节病毒复制。

Nguyen, Lam N; Lim, Yun-Sook; Pham, Long V; Shin, Hae-Young; Kim, Yong-Sun; Hwang, Soon B