Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition
更正：MCC950/CRID3 能有效靶向野生型 NLRP3 的 NACHT 结构域，但不能靶向与疾病相关的突变体，从而抑制炎症小体。
期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.3000529
Walle, Lieselotte Vande; Stowe, Irma B; Šácha, Pavel; Lee, Bettina L; Demon, Dieter; Fossoul, Amelie; Van Hauwermeiren, Filip; Saavedra, Pedro H V; Šimon, Petr; Šubr, Vladimír; Kostka, Libor; Stivala, Craig E; Pham, Victoria C; Staben, Steven T; Yamazoe, Sayumi; Konvalinka, Jan; Kayagaki, Nobuhiko; Lamkanfi, Mohamed
炎症
炎性小体
炎症/感染
ID3
LRP3
NLRP3
炎性小体
免疫/内分泌
