日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Tolerogenic Plasmid Inhibits Autoantibody Production Triggered by Immunization With Human Peptidyl Arginine Deiminase 4

耐受性质粒抑制由人肽基精氨酸脱亚胺酶4免疫诱导的自身抗体产生

Pagni, Philippe P; Kumar, Vijetha; Lambert, Nathalie C; Frison, Eva; Luche, Herve; Mello, Marielle; Torres, Magali; Wesley, Johnna D; von Herrath, Matthias; Roudier, Jean; Auger, Isabelle

A quantitative framework for multiscale analysis of Candida albicans biofilm development

念珠菌生物膜发育多尺度分析的定量框架

Li, Kai; Skivens, Samantha; Green, J Edward F; Tam, Alexander K Y; Pentland, Daniel R; Baumann, Hella; Gourlay, Campbell W; Binder, Benjamin J; Laissue, Philippe P

Core neuromuscular co-activation mechanisms partly explain trunk kinematics in a perturbed postural task

核心神经肌肉协同激活机制可以部分解释受扰姿势任务中的躯干运动学。

Duchene, Youri; Mornieux, Guillaume; Petel, Arthur; Perrin, Philippe P; Gauchard, Gérome C

Unusual outcome variances as a method to identify potentially problematic clinical trials

异常结果差异可作为识别潜在问题临床试验的一种方法

Hujoel, Philippe P; Hujoel, Margaux L A

A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture

化学-遗传相互作用矩阵揭示药物机制和遗传结构

Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Huard, Caroline; Chatr-Aryamontri, Andrew; St-Cyr, Daniel J; Sánchez-Osuna, María; Papadopoli, David; Normandin, Karine; Paydar, Mohammadjavad; McLaughlan, Shannon; St-Denis, Corinne; Zhang, Li; Say, Henry; Palou, Roger; Stark, Chris; Breitkreutz, Bobby-Joe; van der Sloot, Almer M; Manohar, Sandhya; Lavoie, Hugo; Borden, Katherine L B; Raught, Brian; D'Amours, Damien; Sicheri, Frank; Verreault, Alain; Mader, Sylvie; Meloche, Sylvain; Therrien, Marc; Thibault, Pierre; Wilhelm, Brian; Dirks, Peter B; Aitchison, John D; Patton, Elizabeth; King, Randall W; Roux, Philippe P; Sauvageau, Guy; Hoang, Trang; Marinier, Anne; Harrington, Lea; Kwok, Benjamin; Archambault, Vincent; Topisirovic, Ivan; Tyers, Mike

Cell cycle duration determines oncogenic transformation capacity.

细胞周期持续时间决定了其致癌转化能力

Chen Danian, Lu Suying, Huang Katherine, Pearson Joel D, Pacal Marek, Peidis Phillipos, McCurdy Sean, Yu Tao, Sangwan Monika, Nguyen Angela, Monnier Philippe P, Schramek Daniel, Zhu Liang, Santamaria David, Barbacid Mariano, Akeno Nagako, Wikenheiser-Brokamp Kathryn A, Bremner Rod

mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport.

mTOR抑制剂通过诱导替代脂质摄取和促进胆固醇转运来重编程细胞脂质稳态。

Shin Sejeong, Han Min-Joon, Patel Ishika, Welsh Alia M, Sverdlov Maria, Cho Wonhwa, Cologna Stephanie M, Roux Philippe P, Yoon Sang-Oh

IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia.

IL1RAP 是正常核型三突变急性髓系白血病的免疫治疗靶点

Métois Arnaud, Bordeleau Marie-Eve, Theret Louis, Hajmirza Azadeh, Moujaber Ossama, Spinella Jean-François, Chagraoui Jalila, Mayotte Nadine, Boivin Isabel, Audemard Éric, Aubert Léo, Lisi Véronique, Khakipoor Banafsheh, Farah Azer, Bonneil Éric, Robert Alma, Lippens Julie, Moraitis Anna, Béliveau François, Feghaly Albert, Boucher Geneviève, Marcotte Richard, Gendron Patrick, Thibault Pierre, Lemieux Sébastien, Richard-Carpentier Guillaume, Lavallée Vincent-Philippe, Hébert Josée, Roux Philippe P, Sauvageau Guy

EMT-ciliary signaling in quasi-mesenchymal-stem-like cells drives therapeutic resistance and is a druggable vulnerability in triple-negative breast cancer

类间充质干细胞中的EMT纤毛信号传导驱动治疗耐药性,是三阴性乳腺癌的一个可药物靶向的脆弱点。

Camille E Tessier # ,Jennifer Derrien # ,Aurore M M Dupuy ,Thomas Pelé ,Martin Moquet ,Julie Roul ,Elise Douillard ,Camille El Harrif ,Xavier Pinson ,Matthieu Le Gallo ,Florence Godey ,Patrick Tas ,Roselyne Viel ,Eloïse Grasset ,Claude Prigent ,Éric Letouzé ,Peggy Suzanne ,Patrick Dallemagne ,Mario Campone ,Robert A Weinberg ,Jacqueline A Lees ,Philippe P Juin ,Vincent J Guen

Large-scale quantification of stomatal patterning in barley leaves overexpressing epidermal patterning factor 1 reveals differential stomatal density between the adaxial and abaxial surfaces and spatial heterogeneity that impact stomatal function

对过表达表皮模式因子1的大麦叶片进行大规模气孔模式定量分析,揭示了叶片上表面和下表面气孔密度的差异以及影响气孔功能的空间异质性。

Fan, Mengjie; Moss, Keri-Anne; Jindal, Pratham; Kasznicki, Piotr; Davey, Philip; Laissue, Philippe P; Lawson, Tracy