日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ubiquitous expression of an activating mutation in the Pik3ca gene reprograms glucose and lipid metabolism in mice.

Pik3ca 基因中激活突变的普遍表达可重编程小鼠的葡萄糖和脂质代谢

Caiazzo Sabrina, Watt Matthew J, Dodd Garron T, Bayliss Jacqueline, Thomas Helen, Smith Lorey K, Mitchell Camilla B, Phillips Wayne A

Targeting a STING agonist to perivascular macrophages in prostate tumors delays resistance to androgen deprivation therapy.

将 STING 激动剂靶向前列腺肿瘤中的血管周围巨噬细胞,可延缓对雄激素剥夺疗法的耐药性

Al-Janabi Haider, Moyes Katy, Allen Richard, Fisher Matthew, Crespo Mateus, Gurel Bora, Rescigno Pasquale, de Bono Johann, Nunns Harry, Bailey Christopher, Junker-Jensen Anna, Muthana Munitta, Phillips Wayne A, Pearson Helen B, Taplin Mary-Ellen, Brown Janet E, Lewis Claire E

ASO Author Reflections: Are Tumor-Infiltrating Neutrophils Drivers of Metastatic Disease in Esophageal Cancer Patients Treated with Neoadjuvant Therapy?

ASO 作者反思:肿瘤浸润性中性粒细胞是接受新辅助治疗的食管癌患者发生转移性疾病的驱动因素吗?

Cabalag, Carlos S; Phillips, Wayne A; Duong, Cuong P; Clemons, Nicholas J

Potential Clinical Utility of a Targeted Circulating Tumor DNA Assay in Esophageal Adenocarcinoma

靶向循环肿瘤DNA检测在食管腺癌中的潜在临床应用价值

Cabalag, Carlos S; Yates, Michael; Corrales, Mariana Benitez; Yeh, Paul; Wong, Stephen Q; Zhang, Bonnie Z; Fujihara, Kenji M; Chong, Lynn; Hii, Michael W; Dawson, Sarah-Jane; Phillips, Wayne A; Duong, Cuong P; Clemons, Nicholas J

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

GRB7是食管腺癌的致癌驱动基因和潜在治疗靶点。

Gotovac, Jovana R; Liu, David Sh; Yates, Michael J; Milne, Julia V; Macpherson, Arthi A; Simpson, Kaylene J; Eslick, Guy D; Mitchell, Catherine; Duong, Cuong P; Phillips, Wayne A; Clemons, Nicholas J

Mouse Models for Exploring the Biological Consequences and Clinical Significance of PIK3CA Mutations

用于探索PIK3CA突变的生物学后果和临床意义的小鼠模型

Mitchell, Camilla B; Phillips, Wayne A

PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

神经干细胞中PI3K的激活会驱动肿瘤发生,而靶向cAMP反应元件结合蛋白可以缓解这一过程。

Daniel, Paul M; Filiz, Gulay; Brown, Daniel V; Christie, Michael; Waring, Paul M; Zhang, Yi; Haynes, John M; Pouton, Colin; Flanagan, Dustin; Vincan, Elizabeth; Johns, Terrance G; Montgomery, Karen; Phillips, Wayne A; Mantamadiotis, Theo

Inhibiting system x(C)(-) and glutathione biosynthesis - a potential Achilles' heel in mutant-p53 cancers

抑制系统 x(C)(-) 和谷胱甘肽生物合成——突变型 p53 癌症的潜在阿喀琉斯之踵

Clemons, Nicholas J; Liu, David S; Duong, Cuong P; Phillips, Wayne A

Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma

食管腺癌中CIMP样亚型的鉴定及染色体分离和纺锤体组装通路成员的异常甲基化

Krause, Lutz; Nones, Katia; Loffler, Kelly A; Nancarrow, Derek; Oey, Harald; Tang, Yue Hang; Wayte, Nicola J; Patch, Ann Marie; Patel, Kalpana; Brosda, Sandra; Manning, Suzanne; Lampe, Guy; Clouston, Andrew; Thomas, Janine; Stoye, Jens; Hussey, Damian J; Watson, David I; Lord, Reginald V; Phillips, Wayne A; Gotley, David; Smithers, B Mark; Whiteman, David C; Hayward, Nicholas K; Grimmond, Sean M; Waddell, Nicola; Barbour, Andrew P

PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma

PI3激酶抑制剂可延缓BRAF突变型黑色素瘤中MEK1/2抑制剂耐药性的发生。

Deuker, Marian M; Marsh Durban, Victoria; Phillips, Wayne A; McMahon, Martin