日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The unfolded protein response influences therapy outcome and disease progression in chronic lymphocytic leukaemia.

未折叠蛋白反应影响慢性淋巴细胞白血病的治疗结果和疾病进展

Khan Umair Tahir, Clarke Kim, Eagle Gina, Oates Melanie, Hillmen Peter, Jayne Sandrine, Dyer Martin J S, Phipps Alex, Falciani Francesco, Jenkins Rosalind E, Pettitt Andrew R

Population pharmacokinetics and exposure-response analysis of durvalumab in combination with gemcitabine and cisplatin in patients with advanced biliary tract cancer

度伐利尤单抗联合吉西他滨和顺铂治疗晚期胆道癌患者的群体药代动力学和暴露-反应分析

Abegesah, Aburough; Oh, Do-Youn; Lim, KyoungSoo; Fan, Chunling; Chen, Cecil; Kim, Chong; Wang, Julie; Xynos, Ioannis; Zotkiewicz, Magdalena; Ren, Song; Phipps, Alex; Gibbs, Megan; Zhou, Diansong

A mechanistic PK/PD model of AZD0171 (anti-LIF) to support Phase II dose selection

AZD0171(抗LIF)的机制性PK/PD模型,用于支持II期剂量选择

Shahraz, Azar; Penney, Mark; Candido, Juliana; Opoku-Ansah, Grace; Neubauer, Melanie; Eyles, Jim; Ojo, Oluwaseun; Liu, Nelson; Luheshi, Nadia M; Phipps, Alex; Vishwanathan, Karthick

Strategies for clinical dose optimization of T cell-engaging therapies in oncology

肿瘤学中T细胞激活疗法的临床剂量优化策略

Ball, Kathryn; Dovedi, Simon J; Vajjah, Pavan; Phipps, Alex

The potential and pitfalls of artificial intelligence in clinical pharmacology

人工智能在临床药理学中的潜力和陷阱

Johnson, Martin; Patel, Mishal; Phipps, Alex; van der Schaar, Mihaela; Boulton, Dave; Gibbs, Megan

Entrectinib dose confirmation in pediatric oncology patients: pharmacokinetic considerations

儿童肿瘤患者恩曲替尼剂量确认:药代动力学考量

Meneses-Lorente, Georgina; Guerini, Elena; Mercier, Francois; Parrott, Neil; Kowalski, Karey; Chow-Maneval, Edna; Buchheit, Vincent; Bergthold, Guillaume; Fox, Elizabeth; Phipps, Alex; Djebli, Nassim

In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK)

体外和临床研究旨在确定恩曲替尼(一种神经营养酪氨酸受体激酶 (NTRK) 小分子抑制剂)的药物相互作用潜力。

Meneses-Lorente, Georgina; Fowler, Stephen; Guerini, Elena; Kowalski, Karey; Chow-Maneval, Edna; Yu, Li; Mercier, Francois; Ullah, Mohammed; Umehara, Kenichi; Brink, Andreas; Buchheit, Vincent; Zwanziger, Elke; Phipps, Alex; Djebli, Nassim

A Consideration of Fixed Dosing Versus Body Size-Based Dosing Strategies for Chimeric Antigen Receptor T-Cell Therapies

嵌合抗原受体T细胞疗法中固定剂量与基于体型的给药策略的比较研究

He, Jimmy Zhijian; Wang, Hechuan; Lim, KyoungSoo; Ren, Song; Rollins, Fred; Vallaster, Markus; Wong, Ryan; Stebbings, Richard; Standifer, Nathan; Keefe, Robert; Phipps, Alex; Gibbs, Megan

Characterization of the pharmacokinetics of entrectinib and its active M5 metabolite in healthy volunteers and patients with solid tumors

对健康志愿者和实体瘤患者体内恩曲替尼及其活性代谢物M5的药代动力学特征进行研究

Meneses-Lorente, Georgina; Bentley, Darren; Guerini, Elena; Kowalski, Karey; Chow-Maneval, Edna; Yu, Li; Brink, Andreas; Djebli, Nassim; Mercier, Francois; Buchheit, Vincent; Phipps, Alex

Models and Machines: How Deep Learning Will Take Clinical Pharmacology to the Next Level

模型与机器:深度学习如何将临床药理学推向新高度

Hutchinson, Lucy; Steiert, Bernhard; Soubret, Antoine; Wagg, Jonathan; Phipps, Alex; Peck, Richard; Charoin, Jean-Eric; Ribba, Benjamin