日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24

细胞因子IL-17A通过自分泌诱导IL-24驱动的负反馈回路限制Th17细胞的致病性

Wai Po Chong ,Mary J Mattapallil ,Kumarkrishna Raychaudhuri ,So Jin Bing ,Sihan Wu ,Yajie Zhong ,WeiWei Wang ,Zilin Chen ,Phyllis B Silver ,Yingyos Jittayasothorn ,Chi-Chao Chan ,Jun Chen ,Reiko Horai ,Rachel R Caspi

Autoimmunity to neuroretina in the concurrent absence of IFN-γ and IL-17A is mediated by a GM-CSF-driven eosinophilic inflammation

在缺乏IFN-γ和IL-17A的情况下,针对神经视网膜的自身免疫是由GM-CSF驱动的嗜酸性粒细胞炎症介导的。

So Jin Bing ,Phyllis B Silver ,Yingyos Jittayasothorn ,Mary J Mattapallil ,Chi-Chao Chan ,Reiko Horai ,Rachel R Caspi

Interleukin 22 ameliorates neuropathology and protects from central nervous system autoimmunity

白细胞介素 22 可改善神经病理学并预防中枢神经系统自身免疫

Mary J Mattapallil, Jennifer L Kielczewski, Carlos R Zárate-Bladés, Anthony J St Leger, Kumarkrishna Raychaudhuri, Phyllis B Silver, Yingyos Jittayasothorn, Chi-Chao Chan, Rachel R Caspi

AS101 ameliorates experimental autoimmune uveitis by regulating Th1 and Th17 responses and inducing Treg cells

AS101 通过调节 Th1 和 Th17 反应并诱导 Treg 细胞来改善实验性自身免疫性葡萄膜炎

So Jin Bing, Itay Shemesh, Wai Po Chong, Reiko Horai, Yingyos Jittayasothorn, Phyllis B Silver, Benjamin Sredni, Rachel R Caspi

Preparation of Protein-containing Extracts from Microbiota-rich Intestinal Contents

从富含微生物的肠道内容物中制备含蛋白质的提取物

Patricia Dillenburg-Pilla, Carlos R Zárate-Bladés, Phyllis B Silver, Reiko Horai, Rachel R Caspi

Characterization of a New Epitope of IRBP That Induces Moderate to Severe Uveoretinitis in Mice With H-2b Haplotype

IRBP 新表位的表征,该表位在具有 H-2b 单倍型的小鼠中诱发中度至重度葡萄膜视网膜炎

Mary J Mattapallil, Phyllis B Silver, Lizette M Cortes, Anthony J St Leger, Yingyos Jittayasothorn, Jennifer L Kielczewski, James J Moon, Chi-Chao Chan, Rachel R Caspi

Retina-specific T regulatory cells bring about resolution and maintain remission of autoimmune uveitis

视网膜特异性 T 调节细胞可缓解并维持自身免疫性葡萄膜炎的缓解

Phyllis B Silver, Reiko Horai, Jun Chen, Yingyos Jittayasothorn, Chi-Chao Chan, Rafael Villasmil, Muge R Kesen, Rachel R Caspi

IL-27p28 inhibits central nervous system autoimmunity by concurrently antagonizing Th1 and Th17 responses

IL-27p28 通过同时拮抗 Th1 和 Th17 反应来抑制中枢神经系统自身免疫

Wai Po Chong, Reiko Horai #, Mary J Mattapallil #, Phyllis B Silver, Jun Chen, Ru Zhou, Yuri Sergeev, Rafael Villasmil, Chi-Chao Chan, Rachel R Caspi

Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells

视网膜抗原的葡萄膜炎相关表位在人源化小鼠葡萄膜炎模型中具有致病性,并可识别自身攻击性 T 细胞

Mary J Mattapallil, Phyllis B Silver, Joseph J Mattapallil, Reiko Horai, Zaruhi Karabekian, J Hugh McDowell, Chi-Chao Chan, Eddie A James, William W Kwok, H Nida Sen, Robert B Nussenblatt, Chella S David, Rachel R Caspi

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

Th17 或 Th1 效应反应均可驱动自身免疫:疾病诱发条件会影响主要效应类别

Dror Luger, Phyllis B Silver, Jun Tang, Daniel Cua, Zoe Chen, Yoichiro Iwakura, Edward P Bowman, Nicole M Sgambellone, Chi-Chao Chan, Rachel R Caspi