日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Design, synthesis and potent cytotoxic activity of novel 7-(N-[(substituted-sulfonyl)piperazinyl]-methyl)-camptothecin derivatives

新型7-(N-[(取代磺酰基)哌嗪基]-甲基)-喜树碱衍生物的设计、合成及其强效细胞毒活性

Zhu, Gao-Xiang; Cheng, Pi-Le; Goto, Masuo; Zhang, Na; Morris-Natschke, Susan L; Hsieh, Kan-Yen; Yang, Guan-Zhou; Yang, Qian-Ru; Liu, Ying-Qian; Chen, Hai-Le; Zhang, Xiao-Shuai; Lee, Kuo-Hsiung

Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction

通过铜催化三组分反应设计合成新型聚乙二醇偶联的20(S)-喜树碱磺酰脒衍生物,该衍生物具有强效的体外抗肿瘤活性。

Song, Zi-Long; Chen, Hai-Le; Wang, Yu-Han; Goto, Masuo; Gao, Wen-Jing; Cheng, Pi-Le; Morris-Natschke, Susan L; Liu, Ying-Qian; Zhu, Gao-Xiang; Wang, Mei-Juan; Lee, Kuo-Hsiung