Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα
CD47与检查点受体SIRPα之间的顺式相互作用被破坏后,巨噬细胞表现出更高的吞噬水平。
期刊:Journal of Cell Science
影响因子:3.3
doi:10.1242/jcs.237800
Brandon H Hayes ,Richard K Tsai ,Lawrence J Dooling ,Siddhant Kadu ,Justine Y Lee ,Diego Pantano ,Pia L Rodriguez ,Shyamsundar Subramanian ,Jae-Won Shin ,Dennis E Discher
巨噬细胞
细胞生物学
信号转导
免疫/内分泌
巨噬细胞
T细胞
CD4
CD47