日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health

在接受抗逆转录病毒疗法(ART)治疗的SIV感染期间阻断IFN-α可降低组织病毒DNA水平,恢复免疫功能,并改善整体健康状况。

Swainson, Louise A; Sharma, Ashish Arunkumar; Ghneim, Khader; Ribeiro, Susan Pereira; Wilkinson, Peter; Dunham, Richard M; Albright, Rebecca G; Wong, Samson; Estes, Jacob D; Piatak, Michael; Deeks, Steven G; Hunt, Peter W; Sekaly, Rafick-Pierre; McCune, Joseph M

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV

实验性感染 SIV 或 SHIV 的恒河猴的伽马疱疹病毒感染和恶性疾病

Vickie A Marshall, Nazzarena Labo, Xing-Pei Hao, Benjamin Holdridge, Marshall Thompson, Wendell Miley, Catherine Brands, Vicky Coalter, Rebecca Kiser, Miriam Anver, Yelena Golubeva, Andrew Warner, Elaine S Jaffe, Michael Piatak Jr, Scott W Wong, Claes Ohlen, Rhonda MacAllister, Jeremy Smedley, Clair

Early Sites of Virus Replication After Oral SIV(mac251) Infection of Infant Macaques: Implications for Pathogenesis

幼猴口服SIV(mac251)感染后病毒复制的早期位点:对发病机制的启示

Amedee, Angela M; Phillips, Bonnie; Jensen, Kara; Robichaux, Spencer; Lacour, Nedra; Burke, Mark; Piatak, Michael Jr; Lifson, Jeffrey D; Kozlowski, Pamela A; Van Rompay, Koen K A; De Paris, Kristina

An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques

一种可释放三种抗病毒药物和一种避孕药的阴道环,能够阻断SHIV-RT感染,减少HSV-2病毒脱落,并抑制恒河猴的激素周期。

Derby, Nina; Aravantinou, Meropi; Kenney, Jessica; Ugaonkar, Shweta R; Wesenberg, Asa; Wilk, Jolanta; Kizima, Larisa; Rodriguez, Aixa; Zhang, Shimin; Mizenina, Olga; Levendosky, Keith; Cooney, Michael L; Seidor, Samantha; Gettie, Agegnehu; Grasperge, Brooke; Blanchard, James; Piatak, Michael Jr; Lifson, Jeffrey D; Fernández-Romero, José; Zydowsky, Thomas M; Robbiani, Melissa

Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque

接种疫苗的恒河猴中罕见的SIVmac239感染控制

Mauricio A Martins ,Damien C Tully ,Young C Shin ,Lucas Gonzalez-Nieto ,Kim L Weisgrau ,David J Bean ,Rujuta Gadgil ,Martin J Gutman ,Aline Domingues ,Helen S Maxwell ,Diogo M Magnani ,Michael Ricciardi ,Nuria Pedreño-Lopez ,Varian Bailey ,Michael A Cruz ,Noemia S Lima ,Myrna C Bonaldo ,John D Altman ,Eva Rakasz ,Saverio Capuano 3rd ,Keith A Reimann ,Michael Piatak Jr ,Jeffrey D Lifson ,Ronald C Desrosiers ,Todd M Allen ,David I Watkins

Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine

平衡训练有素的免疫力与持续的免疫激活以及接种减毒结核分枝杆菌或牛分枝杆菌 BCG 疫苗的幼年恒河猴感染猿猴免疫缺陷病毒的风险

Kara Jensen, Myra Grace Dela Pena-Ponce, Michael Piatak Jr, Rebecca Shoemaker, Kelli Oswald, William R Jacobs Jr, Glenn Fennelly, Carissa Lucero, Katie R Mollan, Michael G Hudgens, Angela Amedee, Pamela A Kozlowski, Jacob D Estes, Jeffrey D Lifson, Koen K A Van Rompay, Michelle Larsen, Kristina De P

Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

SIVΔnef的持续低水平复制驱动抗体和CD8 T细胞反应的成熟,从而诱导针对阴道SIV感染的保护性免疫

Adnan, Sama; Reeves, R Keith; Gillis, Jacqueline; Wong, Fay E; Yu, Yi; Camp, Jeremy V; Li, Qingsheng; Connole, Michelle; Li, Yuan; Piatak, Michael Jr; Lifson, Jeffrey D; Li, Wenjun; Keele, Brandon F; Kozlowski, Pamela A; Desrosiers, Ronald C; Haase, Ashley T; Johnson, R Paul

Adoptive Transfer of Engineered Rhesus Simian Immunodeficiency Virus-Specific CD8+ T Cells Reduces the Number of Transmitted/Founder Viruses Established in Rhesus Macaques

过继转移工程化的恒河猴免疫缺陷病毒特异性 CD8+ T 细胞可减少恒河猴体内传播/创始病毒的数量

Victor I Ayala, Matthew T Trivett, Eugene V Barsov, Sumiti Jain, Michael Piatak Jr, Charles M Trubey, W Gregory Alvord, Elena Chertova, James D Roser, Jeremy Smedley, Alexander Komin, Brandon F Keele, Claes Ohlen, David E Ott

Vaccine-Elicited Mucosal and Systemic Antibody Responses Are Associated with Reduced Simian Immunodeficiency Viremia in Infant Rhesus Macaques

疫苗诱导的黏膜和全身抗体反应与幼年恒河猴猴免疫缺陷病毒血症的降低相关

Jensen, Kara; Nabi, Rafiq; Van Rompay, Koen K A; Robichaux, Spencer; Lifson, Jeffrey D; Piatak, Michael Jr; Jacobs, William R Jr; Fennelly, Glenn; Canfield, Don; Mollan, Katie R; Hudgens, Michael G; Larsen, Michelle H; Amedee, Angela M; Kozlowski, Pamela A; De Paris, Kristina

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates

急性感染期间细胞因子和趋化因子风暴的强度和性质可区分非人灵长类动物的非进展性和进展性猴免疫缺陷病毒感染

Keating, Sheila M; Heitman, John W; Wu, Shiquan; Deng, Xutao; Stacey, Andrea R; Zahn, Roland C; de la Rosa, Maurus; Finstad, Samantha L; Lifson, Jeffrey D; Piatak, Michael Jr; Gauduin, Marie-Claire; Kessler, Benedikt M; Ternette, Nicola; Carville, Angela; Johnson, R Paul; Desrosiers, Ronald C; Letvin, Norman L; Borrow, Persephone; Norris, Philip J; Schmitz, Joern E