日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Measuring hepatitis B pgRNA stability using an updated automated HBV pgRNA assay with increased sensitivity

利用灵敏度更高的升级版自动化HBV pgRNA检测方法测定乙型肝炎病毒pgRNA的稳定性。

Anderson, Mark; Stec, Michael; Thi, Emily P; Picchio, Gaston; Mbanya, Dora; Cloherty, Gavin

Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB-506 from Phase 1 studies in healthy subjects and those with hepatitis B

在健康受试者和乙型肝炎患者中进行的 I 期研究,评估了衣壳抑制剂 AB-506 的安全性、药代动力学和抗病毒活性。

Yuen, Man-Fung; Berliba, Elina; Sukeepaisarnjaroen, Wattana; Ahn, Sang Hoon; Tanwandee, Tawesak; Lim, Young-Suk; Kim, Yoon Jun; Poovorawan, Kittiyod; Tangkijvanich, Pisit; Schwabe, Christian; Eley, Timothy; Brown, Joanne; Lee, Amy C H; Thi, Emily P; Paratala, Bhavna; Mani, Nagraj; Sofia, Michael J; Picchio, Gaston; Sims, Karen D; Gane, Edward J

An OPTIMIZE study retrospective analysis for management of telaprevir-treated hepatitis C virus (HCV)-infected patients by use of the Abbott RealTime HCV RNA assay

OPTIMIZE 研究采用回顾性分析方法,利用 Abbott RealTime HCV RNA 检测技术,对接受特拉匹韦治疗的丙型肝炎病毒 (HCV) 感染患者进行管理。

Sarrazin, Christoph; Dierynck, Inge; Cloherty, Gavin; Ghys, Anne; Janssen, Katrien; Luo, Donghan; Witek, James; Buti, Maria; Picchio, Gaston; De Meyer, Sandra

Modeling viral evolutionary dynamics after telaprevir-based treatment

模拟特拉匹韦治疗后病毒的进化动力学

Haseltine, Eric L; De Meyer, Sandra; Dierynck, Inge; Bartels, Doug J; Ghys, Anne; Davis, Andrew; Zhang, Eileen Z; Tigges, Ann M; Spanks, Joan; Picchio, Gaston; Kieffer, Tara L; Sullivan, James C

TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1.

TMC278 是一种新一代非核苷类逆转录酶抑制剂 (NNRTI),对野生型和 NNRTI 耐药的 HIV-1 均有效

Azijn Hilde, Tirry Ilse, Vingerhoets Johan, de Béthune Marie-Pierre, Kraus Guenter, Boven Katia, Jochmans Dirk, Van Craenenbroeck Elke, Picchio Gaston, Rimsky Laurence T