日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.

SARS-CoV-2 感染可诱导促纤维化和促血栓形成的泡沫细胞形成。

Battaglia Diana M, Post Claire E, Yao Wenbo, Wahl Angela, Gralinski Lisa E, Liu Hongwei, Dang Hong, Madden Victoria J, White Kristen K, Leist Sarah R, Dinnion Kenneth H 3rd, De la Cruz Gabriela, Midkiff Bentley R, Froggatt Heather M, Gully Kendra, Zweigart Mark, Reader J Rachel, Olstad Katherine J, Everitt Jeffrey I, Van Rompay Koen K A, De Paris Kristina, Sajti Eniko, Pickles Raymond J, Browne Edward P, Jones Corbin D, Boucher Richard C Jr, Baric Ralph S, Garcia J Victor

Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.

长期气道外植体培养能够研究健康、疾病和病毒发病机制

Lee-Ferris Rhianna E, Okuda Kenichi, Galiger Jacob R, Schworer Stephen A, Rogers Troy D, Dang Hong, Gilmore Rodney, Edwards Caitlin, Crisp Gillian, Nakano Satoko, Cawley Anne M, Pickles Raymond J, Gallant Samuel C, Crisci Elisa, Rivier Lauraine, Hagood James S, O'Neal Wanda K, Baric Ralph S, Grubb Barbara R, Boucher Richard C, Randell Scott H

Airway epithelial SARS-CoV-2 infectious and repair responses: relationships to age, sex, and post-COVID pulmonary syndromes

气道上皮细胞对SARS-CoV-2的感染和修复反应:与年龄、性别和COVID-19后肺部综合征的关系

Dang, Hong; Edwards, Caitlin E; Kato, Takafumi; Reidel, Boris; Meganck, Rita M; Esther, Charles R Jr; Ehre, Camille; Fulcher, M Leslie; Bailey, Alexis B; Cooley, Michelle R; Mikami, Yu; Asakura, Takanori; Hawkins, Padraig E; Furusho, Minako; Myers, Jeffrey L; Konopka, Kristine; Gerayeli, Firoozeh V; Park, Hye Yun; Sin, Don D; Livraghi-Butrico, Alessandra; Okuda, Kenichi; Pickles, Raymond J; Klein, Sabra; Randell, Scott H; O'Neal, Wanda K; Baric, Ralph S; Boucher, Richard C

Enhanced susceptibility of pediatric airway epithelium to respiratory syncytial virus infection

儿童气道上皮对呼吸道合胞病毒感染的易感性增强

Pickles, Raymond J; Chen, Gang; Randell, Scott H

Viral airway injury promotes cell engraftment in an in vitro model of cystic fibrosis cell therapy.

病毒性气道损伤促进囊性纤维化细胞治疗体外模型中的细胞植入

Lee Rhianna E, Mascenik Teresa M, Major Sidra C, Galiger Jacob R, Bulik-Sullivan Emily, Siesser Priscila F, Lewis Catherine A, Bear James E, Le Suer Jake A, Hawkins Finn J, Pickles Raymond J, Randell Scott H

RSV infection of humanized lung-only mice induces pathological changes resembling severe bronchiolitis and bronchopneumonia

RSV感染人源化肺移植小鼠可诱发类似于严重细支气管炎和支气管肺炎的病理变化。

De, Chandrav; Pickles, Raymond J; Yao, Wenbo; Liao, Baolin; Boone, Allison; Cleary, Rachel A; Garcia, J Victor; Wahl, Angela

Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein.

基于硫醇的化学探针通过变构破坏刺突糖蛋白中的二硫键,对 SARS-CoV-2 表现出抗病毒活性

Shi Yunlong, Zeida Ari, Edwards Caitlin E, Mallory Michael L, Sastre Santiago, Machado Matías R, Pickles Raymond J, Fu Ling, Liu Keke, Yang Jing, Baric Ralph S, Boucher Richard C, Radi Rafael, Carroll Kate S

Pharmacokinetic-based failure of a detergent virucidal for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) nasal infections: A preclinical study and randomized controlled trial

一项基于药代动力学的去污剂杀病毒剂治疗严重急性呼吸综合征冠状病毒2 (SARS-CoV-2) 鼻腔感染失败的临床前研究和随机对照试验

Esther, Charles R Jr; Kimura, Kyle S; Mikami, Yu; Edwards, Caitlin E; Das, Suman R; Freeman, Michael H; Strickland, Britton A; Brown, Hunter M; Wessinger, Bronson C; Gupta, Veerain C; Von Wahlde, Kate; Sheng, Quanhu; Huang, Li Ching; Bacon, Daniel R; Kimple, Adam J; Ceppe, Agathe S; Kato, Takafumi; Pickles, Raymond J; Randell, Scott H; Baric, Ralph S; Turner, Justin H; Boucher, Richard C

Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19

从过去的失败中吸取教训:新冠肺炎单克隆抗体疗法面临的挑战

Lai, Samuel K; McSweeney, Morgan D; Pickles, Raymond J

SARS-like WIV1-CoV poised for human emergence

类似SARS的WIV1-CoV病毒可能出现于人类

Menachery, Vineet D; Yount, Boyd L Jr; Sims, Amy C; Debbink, Kari; Agnihothram, Sudhakar S; Gralinski, Lisa E; Graham, Rachel L; Scobey, Trevor; Plante, Jessica A; Royal, Scott R; Swanstrom, Jesica; Sheahan, Timothy P; Pickles, Raymond J; Corti, Davide; Randell, Scott H; Lanzavecchia, Antonio; Marasco, Wayne A; Baric, Ralph S