日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NTRK fusions and concomitant immune and genomic landscape detected by DNA and RNA comprehensive genomic profiling in a large healthcare system

在大型医疗保健系统中,通过DNA和RNA综合基因组分析检测到NTRK融合及其伴随的免疫和基因组图谱。

Dowdell, Alexa K; Ward, Thomas R; Hamilton, Lauren T; Weerasinghe, Roshanthi K; Schnettler, Erica; Sathyan, Pratheesh; Roos, Alison; Wagner, Josiah T; Welle, John; Meng, Ryan C; Bartlett, Alexandra Q; Bifulco, Carlo B; Piening, Brian D

Commentary: Molecular responses in pig heart to human xenotransplantation unveiled by longitudinal multi-omic profiling

评论:纵向多组学分析揭示猪心脏对人类异种移植的分子反应

Keating, Brendan J; Schmauch, Eloi; Snyder, Michael P; Motter, Jennifer D; Piening, Brian D

Geno4ME Study: implementation of whole genome sequencing for population screening in a large healthcare system

Geno4ME 研究:在大型医疗保健系统中实施全基因组测序进行人群筛查

Lucas Beckett, Isabelle A; Emery, Kate R; Wagner, Josiah T; Jade, Kathleen; Cosgrove, Benjamin A; Welle, John; Rinaldi, J B; Dickey, Lindsay; Jones, Kyle; Wagner, Nick; Shull, Eric M; Clemens, Jon; Trachana, Kalliopi; Anderson, Lance; Kudla, Allison; Smith, Brett; Verespej, Hakon; Yuan, Li Chi; Denne, Elizabeth; Ramos, Erica; Lovejoy, Jennifer C; Olszewski, Krzysztof; Reese, Martin G; Reynolds, Misty J; Miller, Mandy M; Dowdell, Alexa K; Beck, Brianna; Scanlan, James M; Campbell, Mary B; Magis, Andrew T; Vartanian, Keri; Piening, Brian D; Bifulco, Carlo B; Gordon, Ora K

Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system

设计和验证一种基于全基因组测序的临床检测方法,用于大型医疗保健系统中的患者筛查

Wagner, Josiah T; Welle, John T; Lucas Beckett, Isabelle A; Emery, Kate R; Cosgrove, Benjamin A; Olszewski, Krzysztof; Wagner, Nick; Bower, Tucker C; Yuan, Li Chi; Shull, Eric M; Jade, Kathleen; Clemens, Jon; Magis, Andrew T; Campbell, Mary B; Gordon, Ora K; Bifulco, Carlo B; Piening, Brian D

Widespread Adoption of Precision Anticancer Therapies After Implementation of Pathologist-Directed Comprehensive Genomic Profiling Across a Large US Health System

美国大型医疗系统实施病理学家指导的全面基因组分析后,精准抗癌疗法得到广泛应用。

Dowdell, Alexa K; Meng, Ryan C; Vita, Ann; Bapat, Bela; Hanes, Douglas; Chang, Shu-Ching; Harold, Lauren; Wong, Cliff; Poon, Hoifung; Schroeder, Brock; Weerasinghe, Roshanthi; Leidner, Rom; Urba, Walter J; Bifulco, Carlo B; Piening, Brian D

Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer

同时发生的导管原位癌和浸润性乳腺癌的多组学分析

Kaplan, Henry G; Dowdell, Alexa K; Berry, Anna B; Shimol, Racheli Ben; Robinson, Fred L; Carney, Christopher A; Piening, Brian D

Myeloid MyD88 restricts CD8(+) T cell response to radiation therapy in pancreatic cancer

髓系MyD88限制胰腺癌中CD8(+) T细胞对放射治疗的反应

Medler, Terry R; Blair, Tiffany C; Alice, Alejandro F; Dowdell, Alexa K; Piening, Brian D; Crittenden, Marka R; Gough, Michael J

Whole transcriptome profiling of prospective endomyocardial biopsies reveals prognostic and diagnostic signatures of cardiac allograft rejection

对前瞻性心内膜活检标本进行全转录组分析,揭示了心脏移植排斥反应的预后和诊断特征。

Piening, Brian D; Dowdell, Alexa K; Zhang, Mengqi; Loza, Bao-Li; Walls, David; Gao, Hui; Mohebnasab, Maede; Li, Yun Rose; Elftmann, Eric; Wei, Eric; Gandla, Divya; Lad, Hetal; Chaib, Hassan; Sweitzer, Nancy K; Deng, Mario; Pereira, Alexandre C; Cadeiras, Martin; Shaked, Abraham; Snyder, Michael P; Keating, Brendan J

Gut microbiota analyses of Saudi populations for type 2 diabetes-related phenotypes reveals significant association

对沙特阿拉伯人群肠道菌群与2型糖尿病相关表型的分析揭示了显著关联。

Al-Muhanna, Fahad A; Dowdell, Alexa K; Al Eleq, Abdulmohsen H; Albaker, Waleed I; Brooks, Andrew W; Al-Sultan, Ali I; Al-Rubaish, Abdullah M; Alkharsah, Khaled R; Sulaiman, Raed M; Al-Quorain, Abdulaziz A; Cyrus, Cyril; Alali, Rudaynah A; Vatte, Chittibabu; Robinson, Fred L; Zhou, Xin; Snyder, Michael P; Almuhanna, Afnan F; Keating, Brendan J; Piening, Brian D; Al-Ali, Amein K

Trough levels of ipilimumab in serum as a potential biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab.

血清中伊匹木单抗谷浓度可作为晚期黑色素瘤患者接受伊匹木单抗治疗后临床疗效的潜在生物标志物

Koguchi Yoshinobu, Iwamoto Noriko, Shimada Takashi, Chang Shu-Ching, Cha John, Curti Brendan D, Urba Walter J, Piening Brian D, Redmond William L