日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combining xQTL and genome-wide association studies from diverse populations improves druggable gene discovery

结合来自不同人群的 xQTL 和全基因组关联研究,可以提高药物靶向基因的发现效率。

Lorincz-Comi, Noah; Song, Wenqiang; Chen, Xin; Paz, Isabela Rivera; Hou, Yuan; Zhou, Yadi; Xu, Jielin; Martin, William; Barnard, John; Pieper, Andrew A; Haines, Jonathan L; Chung, Mina K; Cheng, Feixiong

P7C3-A20 prevents whole brain radiotherapy-induced chronic hippocampal redox imbalance and neuropsychiatric impairment in mice

P7C3-A20可预防小鼠全脑放射治疗引起的慢性海马氧化还原失衡和神经精神损伤。

Vázquez-Rosa, Edwin; Shin, Min-Kyoo; Chaubey, Kalyani; Barker, Sarah; Corella, Sofia G; Chakraborty, Suwarna; Tripathi, Sunil Jamuna; Yu, Youngmin; Hyung, Jiwon; Dashora, Himanshu; Hao, Jing; Cintrón-Pérez, Coral J; Bud, Zea; Dhar, Matasha; Miller, Emiko; Koh, Yeojung; Lindley, Kate P; Indrakumar, Vidya; Rodriguez, Rocio Aguila; Mapuskar, Kranti A; Schoenfeld, Joshua D; Fujioka, Hisashi; Szweda, Luke I; Wilson, Brigid M; Yu, Jennifer S; Paul, Bindu D; Spitz, Douglas R; Allen, Bryan G; Pieper, Andrew A

Hydrogen sulfide signalling in neurodegenerative diseases

神经退行性疾病中的硫化氢信号传导

Tripathi, Sunil Jamuna; Chakraborty, Suwarna; Miller, Emiko; Pieper, Andrew A; Paul, Bindu D

Network-based prediction and real-world patient data observation identify doxycycline as a repurposable drug in Alzheimer's disease

基于网络预测和真实世界患者数据观察的研究表明,多西环素可作为阿尔茨海默病的一种可再利用药物。

Bykova, Marina; Karavani, Ehud; Danziger, Michael; Tonegawa-Kuji, Reina; Martin, William; Sha, Zhendong; Pieper, Andrew A; Rosen-Zvi, Michal; Cheng, Feixiong

Advances in neuropsychiatry: From objective diagnostics to mechanism-based therapeutics

神经精神病学进展:从客观诊断到基于机制的治疗

Pieper, Andrew A; Lee, Francis S

Critical evaluation of real-world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation

利用目标试验模拟对阿尔茨海默病药物研发管线中可再利用药物的真实世界证据进行批判性评估

Tonegawa-Kuji, Reina; Karavani, Ehud; Danziger, Michael; Zhang, Pengyue; Hou, Yuan; Zhou, Yadi; Bykova, Marina; Pieper, Andrew A; Rosen-Zvi, Michal; Cummings, Jeffrey; Cheng, Feixiong

Bringing to Light the Invisible Lymphatic Anatomy of the Upper Extremity: Report From the 2024 Harvard Radcliffe Institute Accelerator Workshop

揭示上肢隐秘的淋巴解剖结构:2024年哈佛拉德克利夫学院加速器研讨会报告

Fanning, James E; Tsai, Leo L; Amore, Miguel A; Crescenzi, Rachelle; De Paepe, Katja N; Donohoe, Kevin J; Maki, Jeffrey H; Padera, Timothy P; Pieper, Claus C; Reynolds, Hayley M; Suami, Hiroo; Singhal, Dhruv

Cell type-specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease

细胞类型特异性基因调控图谱优先考虑阿尔茨海默病中的药物靶点和可再利用药物

Ren, Yunxiao; Hu, Ming; Li, Yang E; Pieper, Andrew A; Cummings, Jeffrey; Cheng, Feixiong

Associations of depressive symptoms and antidepressant medication use with physical function among middle-aged adults: Results from the CARDIA Function study

抑郁症状和抗抑郁药物使用与中年人身体功能之间的关联:CARDIA 功能研究的结果

Burrows, Brett T; Sloane, Richard; Ashner, Marissa C; Pieper, Carl F; Lewis, Cora E; Gabriel, Kelley Pettee; Schreiner, Pamela J; Hornikel, Bjoern; Zhang, Kai; Jenkins, Nathaniel D M; Sullivan, Angela; Bowling, C Barrett

Clinical validation of T1ρ mapping for the assessment of hepatic fibrosis in patients with chronic liver disease

T1ρ mapping在慢性肝病患者肝纤维化评估中的临床验证

Mesropyan, Narine; Chang, Johannes; Lutz, Philipp; Kaiser, Felix; Weber, Oliver M; Katemann, Christoph; Dell, Tatjana; Kravchenko, Dmitrij; Yueksel, Can; Kuetting, Daniel; Pieper, Claus C; Luetkens, Julian A; Isaak, Alexander