日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

STRATEGIC-1: multiple-line, randomized, open-label GERCOR-PRODIGE-39 phase III trial in unresectable RAS/BRAF wild-type metastatic colorectal cancer

STRATEGIC-1：一项针对不可切除的 RAS/BRAF 野生型转移性结直肠癌的多线、随机、开放标签的 GERCOR-PRODIGE-39 III 期试验

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02639-y
Chibaudel, Benoist; Dourthe, Louis-Marie; André, Thierry; Henriques, Julie; Bourgeois, Vincent; Etienne, Pierre-Luc; Desramé, Jérôme; Carola, Elisabeth; Dupuis, Olivier; Baba-Hamed, Nabil; Auby, Dominique; Louvet, Christophe; Maillard, Emmanuel; Romano, Olivier; Tournigand, Christophe; Garcia-Larnicol, Marie-Line; Shacham-Shmueli, Einat; Bird, Brian Healey; Ghiringhelli, François; de Gramont, Aimery
肿瘤
肠癌
肿瘤免疫
PROD
BRAF
IGE
RAS
发表日期：2026
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A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function

神经降压素受体1型衍生肽素作为一种偏向性变构调节剂，可调节靶受体功能。

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.12.043
Brouillette, Rebecca L; Lussier, Frédérique; Breault, Émile; Meneboo, Nathan; Hassanzadeh, Malihe; Tremblay, Victoria; Chartier, Magali; Midavaine, Élora; Ulrich, Laurence; Côté, Jérôme; Blais, Véronique; Mona, Christine E; Longpré, Jean-Michel; Grandbois, Michel; Boudreault, Pierre-Luc; Audet, Martin; Besserer-Offroy, Élie; Sarret, Philippe
信号转导
发表日期：2026
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TMPRSS2 inhibitors with broad-spectrum efficacy against SARS-CoV-2 (JN.1) and influenza A (H1N1) viruses protect mice from influenza A infection

TMPRSS2抑制剂对SARS-CoV-2（JN.1）和甲型流感（H1N1）病毒具有广谱疗效，并能保护小鼠免受甲型流感病毒感染。

期刊:Emerging Microbes & Infections
影响因子:7.5
doi:10.1080/22221751.2026.2616944
Presley, Lianne; Pérez-Vargas, Jimena; Saintigny, Anaïs; Villanueva, Iván; Ho, Michelle; Fone, Jessica; Brinsden, Lara; Kaushik, Nidhi; Olver, Syan; Thompson, Connor A H; Bautista-Sánchez, Diana; Ennis, Siobhan; Chen, Mike; McCallum, Matthew; Brown, Jack T; Ferková, Sára; Hetrick, Brian; Veesler, David; Leduc, Richard; Niikura, Masahiro; Boudreault, Pierre-Luc; Warner, Bryce; Jean, François
炎症/感染
流感
SARS-CoV-2
微生物学
发表日期：2026
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Tunable Biased Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Engineering and Allosteric Site Targeting

通过C端肽工程和变构位点靶向调控血管紧张素II 1型受体的正性肌力信号传导

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c01259
Hadjadj, Margot; Hassanzadeh, Malihe; Martel, Justin; Roy, Marie-Frédérique; Giguère, Hugo; Murza, Alexandre; Holleran, Brian J; Namkung, Yoon; Froehlich, Ulrike; Leduc, Richard; Auger-Messier, Mannix; Laporte, Stéphane A; Boudreault, Pierre-Luc
信号转导
发表日期：2026
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Androgen Receptor Point Mutations: A Mechanism of Therapeutic Resistance and a Framework for Rational Drug Design

雄激素受体点突变：一种治疗耐药机制和合理药物设计的框架

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers18061043
Colah, Avan; Ferková, Sára; Zhang, Han; Liu, Glenn; MacGillivray, Leonard; Boudreault, Pierre-Luc; Ricke, William
信号转导
治疗耐药
免疫/内分泌
发表日期：2026
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Identification of skeletal muscle stem cell adhesion motifs using spot-synthesis-based peptide arrays.

利用基于点合成的肽阵列鉴定骨骼肌干细胞粘附基序。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114498
Leblanc Elizabeth, Schüler Svenja C, Liu Yuguo, Théroux Léa, Le Moal Emmeran, Bonin Marc-André, Boudreault Pierre-Luc, Bentzinger C Florian
发育与干细胞
干细胞
发表日期：2026
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Biosensor-guided discovery of peptide inhibitors targeting the ribosomal protein uS5-PDCD2 chaperone interaction

生物传感器引导的靶向核糖体蛋白uS5-PDCD2分子伴侣相互作用的肽抑制剂的发现

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2026.111415
Mir Hassani, Zabih; Goulet, Frédérique; Nguyen, Duc Tai; Landry-Voyer, Anne-Marie; Kwiatek, Lauren; Gaudet, Shany; Boudreault, Pierre-Luc; Azad, Taha; Bachand, François
CD2
发表日期：2026
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Immediate Postoperative Evolution of Cerebral Doppler and Saturation Parameters After Cardiopulmonary Bypass in Infants With Congenital Heart Disease: A Prospective Cohort Study

先天性心脏病患儿体外循环术后脑多普勒和血氧饱和度参数的即刻术后变化：一项前瞻性队列研究

期刊:Critical Care Explorations
影响因子:2.7
doi:10.1097/CCE.0000000000001364
Mir, Marina; Maitre, Guillaume; Dancea, Adrian; Bernier, Pierre-Luc; Fontela, Patricia; Zavalkoff, Samara; Roche Martínez, Ana; O'Brien, Nicole; LaRovere, Kerri L; Shemie, Sam D; Altit, Gabriel
心脏病
心血管
神经科学
发表日期：2026
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A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)

妊娠期原发性醛固酮增多症影响的回顾性研究（HAPPI 研究组）

期刊:Clinical Endocrinology
影响因子:2.4
doi:10.1111/cen.70051
Oprea, Diana; Lefrançois, Frédérique; St-Jean, Matthieu; Côté, Anne-Marie; Roy-Lacroix, Marie-Ève; Malick, Mandy; Mallet, Pierre-Luc; Sauvé, Nadine
醛固酮增多症
APP
免疫/内分泌
发表日期：2026
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PARADIM: A Platform to Support Research at the Interface of Data Science and Medical Imaging

PARADIM：一个支持数据科学与医学影像交叉领域研究的平台

期刊:
影响因子:
doi:10.1007/s10278-025-01554-y
Lemaréchal, Yannick; Couture, Gabriel; Pelletier, François; Lefol, Ronan; Asselin, Pierre-Luc; Ouellet, Samuel; Bernard, Jérémie; Ebrahimpour, Leyla; Manem, Venkata S K; Topalis, Johanna; Schachtner, Balthasar; Jodogne, Sébastien; Joubert, Philippe; Jeblick, Katharina; Ingrisch, Michael; Després, Philippe
发表日期：2026
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