Splice-switch oligonucleotide-based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC-driven hepatocellular carcinoma
基于剪接开关寡核苷酸的组合平台优先靶向合成致死靶点 CHK1 和 BRD4,以对抗 MYC 驱动的肝细胞癌。
期刊:Bioengineering & Translational Medicine
影响因子:5.7
doi:10.1002/btm2.10363
Thng, Dexter Kai Hao; Toh, Tan Boon; Pigini, Paolo; Hooi, Lissa; Dan, Yock Young; Chow, Pierce Kah-Hoe; Bonney, Glenn Kunnath; Rashid, Masturah Bte Mohd Abdul; Guccione, Ernesto; Wee, Dave Keng Boon; Chow, Edward Kai-Hua