日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiple disulfide-bonded states confer extensive conformational diversity in fibrinogen

多种二硫键结合状态赋予纤维蛋白原广泛的构象多样性。

Pijning, Aster E; Butera, Diego; Hogg, Philip J

Patient anti-FVIII drug antibodies bind preferentially to a subset of FVIII covalent states.

患者抗FVIII药物抗体优先与FVIII共价状态的子集结合

Butera Diego, Pijning Aster E, Avery Nathan G, Coxon Carmen H, Metcalfe Clive, Mimoun Angelina, Lacroix-Desmazes Sébastien, Spiegel Paul Clint Jr, Hogg Philip J

Unprecedented Diversity of the Glycoside Hydrolase Family 70: A Comprehensive Analysis of Sequence, Structure, and Function

糖苷水解酶70家族前所未有的多样性:序列、结构和功能的全面分析

Pijning, Tjaard; Dijkhuizen, Lubbert

Structural and time-resolved mechanistic investigations of protein hydrolysis by the acidic proline-specific endoprotease from Aspergillus niger

黑曲霉酸性脯氨酸特异性内切蛋白酶水解蛋白质的结构和时间分辨机制研究

Tjaard Pijning, Andreja Vujičić-Žagar, Jan-Metske van der Laan, René M de Jong, Carlos Ramirez-Palacios, Andre Vente, Luppo Edens, Bauke W Dijkstra

Crystal Structure of 4,6-α-Glucanotransferase GtfC-ΔC from Thermophilic Geobacillus 12AMOR1: Starch Transglycosylation in Non-Permuted GH70 Enzymes

嗜热土芽孢杆菌 12AMOR1 的 4,6-α-葡聚糖转移酶 GtfC-ΔC 的晶体结构:非置换 GH70 酶中的淀粉转糖基化

Tjaard Pijning, Evelien M Te Poele, Tijn C de Leeuw, Albert Guskov, Lubbert Dijkhuizen

An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function

血小板 αIIbβ3 整合素的另一种共价形式,位于粘着斑中,功能发生改变

Aster E Pijning, Mitchell T Blyth, Michelle L Coote, Freda Passam, Joyce Chiu, Philip J Hogg

Insights into Broad-Specificity Starch Modification from the Crystal Structure of Limosilactobacillus Reuteri NCC 2613 4,6-α-Glucanotransferase GtfB

从 Reuteri 乳酸杆菌 NCC 2613 4,6-α-葡聚糖转移酶 GtfB 的晶体结构洞察广谱淀粉改性

Tjaard Pijning, Joana Gangoiti, Evelien M Te Poele, Tim Börner, Lubbert Dijkhuizen

Using Mutability Landscapes To Guide Enzyme Thermostabilization

利用变异性景观指导酶的热稳定性

Guo, Chao; Ni, Yan; Biewenga, Lieuwe; Pijning, Tjaard; Thunnissen, Andy-Mark W H; Poelarends, Gerrit J

Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

利用定制的人工迈克尔酶在一锅级联反应中对映选择性合成具有药用活性的γ-氨基丁酸

Biewenga, Lieuwe; Saravanan, Thangavelu; Kunzendorf, Andreas; van der Meer, Jan-Ytzen; Pijning, Tjaard; Tepper, Pieter G; van Merkerk, Ronald; Charnock, Simon J; Thunnissen, Andy-Mark W H; Poelarends, Gerrit J

Identification of Thermotoga maritima MSB8 GH57 α-amylase AmyC as a glycogen-branching enzyme with high hydrolytic activity

鉴定出海洋嗜热菌 MSB8 GH57 α-淀粉酶 AmyC 是一种具有高水解活性的糖原分支酶

Xuewen Zhang, Hans Leemhuis, Štefan Janeček, Mária Martinovičová, Tjaard Pijning, Marc J E C van der Maarel