日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice

在阿尔茨海默病中,铁相关的脂质过氧化作用在脂筏中增强,而铁死亡抑制因子减少,这一现象已通过小鼠螯合实验得到证实。

Thorwald, Max A; Godoy-Lugo, Jose A; Garcia, Gilberto; Silva, Justine; Kim, Minhoo; Christensen, Amy; Mack, Wendy J; Head, Elizabeth; O'Day, Peggy A; Benayoun, Bérénice A; Morgan, Todd E; Pike, Christian J; Higuchi-Sanabria, Ryo; Forman, Henry Jay; Finch, Caleb E

Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner

小胶质细胞/巨噬细胞特异性敲除TLR-4能够以性别二态性的方式保护神经系统免受饮食诱导肥胖的影响。

Liu, Jiahui; Zaidi, Ali; Pike, Christian J

Androgens Regulate Tau Phosphorylation Through Phosphatidylinositol 3-Kinase-Protein Kinase B-Glycogen Synthase Kinase 3β Signaling

雄激素通过磷脂酰肌醇3-激酶-蛋白激酶B-糖原合成酶激酶3β信号通路调节Tau蛋白磷酸化

Yao, Mingzhong; Rosario, Emily R; Soper, Jenna Carroll; Pike, Christian J

Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice.

在中年雄性小鼠中,通过促进寿命的干预措施 17α-雌二醇来预防 APOE4 相关表型

McGill Cassandra J, Christensen Amy, Qian Wenjie, Thorwald Max A, Lugo Jose Godoy, Namvari Sara, White Olivia S, Finch Caleb E, Benayoun Bérénice A, Pike Christian J

Effects of obesogenic diet and 17β-estradiol in female mice with APOE 3/3, 3/4, and 4/4 genotypes

肥胖饮食和17β-雌二醇对APOE 3/3、3/4和4/4基因型雌性小鼠的影响

Christensen, Amy; McGill, Cassandra J; Qian, Wenjie; Pike, Christian J

Apolipoprotein E polymorphisms and female fertility in a transgenic mouse model of Alzheimer's disease

载脂蛋白E多态性与阿尔茨海默病转基因小鼠模型雌性生育力的关系

Medegan Fagla, Bani; York, Jason; Christensen, Amy; Dela Rosa, Cielo; Balu, Deebika; Pike, Christian J; Tai, Leon M; Buhimschi, Irina A

Role of estrogen in women's Alzheimer's disease risk as modified by APOE

雌激素在女性阿尔茨海默病风险中的作用及其受APOE基因的影响

Valencia-Olvera, Ana C; Maldonado Weng, Juan; Christensen, Amy; LaDu, Mary Jo; Pike, Christian J

Aging Reduces Estradiol Protection Against Neural but Not Metabolic Effects of Obesity in Female 3xTg-AD Mice

衰老会降低雌二醇对肥胖引起的神经系统影响的保护作用,但不会降低其对代谢的影响(在雌性 3xTg-AD 小鼠中)。

Christensen, Amy; Liu, Jiahui; Pike, Christian J

Second to fourth digit ratio (2D:4D) is associated with dementia in women

第二指与第四指长度比(2D:4D)与女性痴呆症相关。

Jiang, Joanne; Young, Katherine; Pike, Christian J

Effects of aging, high-fat diet, and testosterone treatment on neural and metabolic outcomes in male brown Norway rats

衰老、高脂饮食和睾酮治疗对雄性褐挪威大鼠神经和代谢结果的影响

Moser, V Alexandra; Christensen, Amy; Liu, Jiahui; Zhou, Amanda; Yagi, Shunya; Beam, Christopher R; Galea, Liisa; Pike, Christian J