日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity.

肠致病性大肠杆菌毒素 EspC 的晶体结构揭示了控制宿主细胞进入和细胞毒性的机制

Pilapitiya Akila U, Hor Lilian, Pan Jing, Wijeyewickrema Lakshmi C, Pike Robert N, Leyton Denisse L, Paxman Jason J, Heras Begoña

Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods

二十年来,生物信息学在蛋白酶特异性底物和切割位点预测方面的研究:对现有方法的全面回顾和基准测试

Li, Fuyi; Wang, Yanan; Li, Chen; Marquez-Lago, Tatiana T; Leier, André; Rawlings, Neil D; Haffari, Gholamreza; Revote, Jerico; Akutsu, Tatsuya; Chou, Kuo-Chen; Purcell, Anthony W; Pike, Robert N; Webb, Geoffrey I; Ian Smith, A; Lithgow, Trevor; Daly, Roger J; Whisstock, James C; Song, Jiangning

Molecular basis for the folding of β-helical autotransporter passenger domains

β螺旋自转运蛋白乘客结构域折叠的分子基础

Yuan, Xiaojun; Johnson, Matthew D; Zhang, Jing; Lo, Alvin W; Schembri, Mark A; Wijeyewickrema, Lakshmi C; Pike, Robert N; Huysmans, Gerard H M; Henderson, Ian R; Leyton, Denisse L

PROSPERous: high-throughput prediction of substrate cleavage sites for 90 proteases with improved accuracy

PROSPERous:高通量预测90种蛋白酶的底物切割位点,并提高了预测准确性

Song, Jiangning; Li, Fuyi; Leier, André; Marquez-Lago, Tatiana T; Akutsu, Tatsuya; Haffari, Gholamreza; Chou, Kuo-Chen; Webb, Geoffrey I; Pike, Robert N; Hancock, John

Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway

疥螨的非活性丝氨酸蛋白酶是人补体凝集素途径的强效抑制剂。

Reynolds, Simone L; Pike, Robert N; Mika, Angela; Blom, Anna M; Hofmann, Andreas; Wijeyewickrema, Lakshmi C; Kemp, Dave; Fischer, Katja

Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS

霍乱弧菌等细菌中发现的II型分泌系统的组装依赖于新型的Pilotin AspS蛋白。

Dunstan, Rhys A; Heinz, Eva; Wijeyewickrema, Lakshmi C; Pike, Robert N; Purcell, Anthony W; Evans, Timothy J; Praszkier, Judyta; Robins-Browne, Roy M; Strugnell, Richard A; Korotkov, Konstantin V; Lithgow, Trevor

Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells

Tax蛋白诱导的抗凋亡蛋白Bfl-1的表达有助于人类T细胞白血病病毒1型(HTLV-1)感染的T细胞的存活。

Zhang, Yi-Ya; Huang, Yong; He, Quan-Ze; Luo, Ji; Zhu, Li; Lu, Shan-Shan; Liu, Jin-Yan; Huang, Peng-Fei; Zeng, Xiong-Zhi; Liang, Song-Ping; Zhao, Peishen; Lieu, TinaMarie; Barlow, Nicholas; Metcalf, Matthew; Veldhuis, Nicholas; Jensen, Dane D; Kocan, Martina; Sostegni, Silvia; Haerteis, Silke; Baraznenok, Vera; Henderson, Ian; Lindström, Erik; Guerrero-Alba, Raquel; Valdez-Morales, Eduardo E; Liedtke, Wolfgang; McIntyre, Peter; Vanner, Stephen J; Korbmacher, Christoph; Bunnett, Nigel W; Pero, Raffaela; Palmieri, Dario; Angrisano, Tiziana; Valentino, Teresa; Federico, Antonella; Franco, Renato; Lembo, Francesca; Klein-Szanto, Andres J; Del Vecchio, Luigi; Montanaro, Donatella; Keller, Simona; Arra, Claudio; Papadopoulou, Vasiliki; Wagner, Simon D; Croce, Carlo M; Fusco, Alfredo; Chiariotti, Lorenzo; Fedele, Monica; Hong, Lin; Kenney, S Ray; Phillips, Genevieve K; Simpson, Denise; Schroeder, Chad E; Nöth, Julica; Romero, Elsa; Swanson, Scarlett; Waller, Anna; Strouse, J Jacob; Carter, Mark; Chigaev, Alexandre; Ursu, Oleg; Oprea, Tudor; Hjelle, Brian; Golden, Jennifer E; Aubé, Jeffrey; Hudson, Laurie G; Buranda, Tione; Sklar, Larry A; Wandinger-Ness, Angela; Yongqing, Tang; Wilmann, Pascal G; Reeve, Shane B; Coetzer, Theresa H; Smith, A Ian; Whisstock, James C; Pike, Robert N; Wijeyewickrema, Lakshmi C; Shilling, Dustin; Foskett, J Kevin; Marchant, Jan; Cowper, Ben; Liu, Yan; Lai, Livia; Pinzan, Camila; Marq, Jean Baptiste; Friedrich, Nikolas; Sawmynaden, Kovilen; Liew, Lloyd; Chai, Wengang; Childs, Robert A; Saouros, Savvas; Simpson, Peter; Roque Barreira, Maria Cristina; Feizi, Ten; Soldati-Favre, Dominique; Matthews, Stephen; Macaire, Héloïse; Riquet, Aurélien; Moncollin, Vincent; Biémont-Trescol, Marie-Claude; Duc Dodon, Madeleine; Hermine, Olivier; Debaud, Anne-Laure; Mahieux, Renaud; Mesnard, Jean-Michel; Pierre, Marlène; Gazzolo, Louis; Bonnefoy, Nathalie; Valentin, Hélène

Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni

利用载体RNA干扰抑制曼氏血吸虫中的组织蛋白酶B1

Tchoubrieva, Elissaveta B; Ong, Poh C; Pike, Robert N; Brindley, Paul J; Kalinna, Bernd H

Assessing the impact of topography on malaria exposure and malaria epidemic sensitivity in the Western Kenya highlands

评估地形对肯尼亚西部高地疟疾暴露和疟疾流行敏感性的影响

Kennan, Ruth M; Wong, Wilson; Dhungyel, Om P; Han, Xiaoyan; Wong, David; Parker, Dane; Rosado, Carlos J; Law, Ruby H P; McGowan, Sheena; Reeve, Shane B; Levina, Vita; Powers, Glenn A; Pike, Robert N; Bottomley, Stephen P; Smith, A Ian; Marsh, Ian; Whittington, Richard J; Whisstock, James C; Porter, Corrine J; Rood, Julian I; Wanjala, Christine L; Githeko, Andrew K; Waitumbi, John N

Protease-activated receptor 2 has pivotal roles in cellular mechanisms involved in experimental periodontitis

蛋白酶激活受体2在实验性牙周炎的细胞机制中起着关键作用

Wong, David M; Tam, Vivian; Lam, Roselind; Walsh, Katrina A; Tatarczuch, Liliana; Pagel, Charles N; Reynolds, Eric C; O'Brien-Simpson, Neil M; Mackie, Eleanor J; Pike, Robert N