日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Retinal phenotype of APOB100 transgenic mice on a Western diet with human-like hyperlipidemia and cholesterol crystals in the retina and choroid

喂食西式饮食的APOB100转基因小鼠的视网膜表型表现为类似人类的高脂血症,视网膜和脉络膜中出现胆固醇结晶。

El-Darzi, Nicole; Dorweiler, Tim F; Mast, Natalia; Busik, Julia; Pikuleva, Irina A

Dietary effects on the retina of hamsters.

饮食对仓鼠视网膜的影响

El-Darzi Nicole, Mast Natalia, Li Yong, Pikuleva Irina A

Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters

仓鼠视网膜和大脑中胆固醇相关通路定量表征

Mast, Natalia; El-Darzi, Nicole; Li, Yong; Pikuleva, Irina A

Challenges and Opportunities in P450 Research on the Eye

P450眼科研究的挑战与机遇

Pikuleva, Irina A

The Hydroxylation Position Rather than Chirality Determines How Efavirenz Metabolites Activate Cytochrome P450 46A1 In Vitro

羟基化位置而非手性决定了依非韦伦代谢物如何在体外激活细胞色素P450 46A1

Mast, Natalia; Fotinich, Anna; Pikuleva, Irina A

Cholesterol Hydroxylating Cytochrome P450 46A1: From Mechanisms of Action to Clinical Applications

胆固醇羟化细胞色素P450 46A1:从作用机制到临床应用

Pikuleva, Irina A; Cartier, Nathalie

Targeting cytochrome P450 46A1 and brain cholesterol 24-hydroxylation to treat neurodegenerative diseases

靶向细胞色素P450 46A1和脑胆固醇24-羟基化治疗神经退行性疾病

Pikuleva, Irina A

CYP46A1-dependent and independent effects of efavirenz treatment

依非韦伦治疗的CYP46A1依赖性和非依赖性效应

Mast, Natalia; El-Darzi, Nicole; Petrov, Alexey M; Li, Young; Pikuleva, Irina A

Cholesterol 24-Hydroxylation by CYP46A1: Benefits of Modulation for Brain Diseases

CYP46A1介导的胆固醇24-羟基化:调节该过程对脑部疾病的益处

Petrov, Alexey M; Pikuleva, Irina A

The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment

在依非韦伦治疗降低淀粉样蛋白的模式中,依非韦伦激活的CYP46A1影响的关键基因、磷酸化蛋白、过程和通路。

Petrov, Alexey M; Mast, Natalia; Li, Yong; Pikuleva, Irina A