日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice

IL-23 促进 BXD2 小鼠中 B 细胞生发中心协调程序,以实现 IgG2b 的类别转换重组

Huixian Hong, Min Gao, Qi Wu, PingAr Yang, Shanrun Liu, Hao Li, Peter D Burrows, Daniel Cua, Jake Y Chen, Hui-Chen Hsu, John D Mountz

Cutting Edge: Intracellular IFN-β and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells

前沿:循环系统性红斑狼疮 B 细胞中的细胞内 IFN-β 和不同的 I 型 IFN 表达模式

Jennie A Hamilton, Qi Wu, PingAr Yang, Bao Luo, Shanrun Liu, Jun Li, Alexa L Mattheyses, Ignacio Sanz, W Winn Chatham, Hui-Chen Hsu, John D Mountz

Cutting Edge: Endogenous IFN-β Regulates Survival and Development of Transitional B Cells

前沿:内源性 IFN-β 调节过渡 B 细胞的存活和发育

Jennie A Hamilton, Qi Wu, PingAr Yang, Bao Luo, Shanrun Liu, Huixian Hong, Jun Li, Mark R Walter, Eleanor N Fish, Hui-Chen Hsu, John D Mountz

Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus

干扰素诱导的机械感知缺陷会阻碍狼疮中凋亡细胞的清除

Hao Li, Yang-Xin Fu, Qi Wu, Yong Zhou, David K Crossman, PingAr Yang, Jun Li, Bao Luo, Laurence M Morel, Janusz H Kabarowski, Hideo Yagita, Carl F Ware, Hui-Chen Hsu, John D Mountz

General Approach for Tetramer-Based Identification of Autoantigen-Reactive B Cells: Characterization of La- and snRNP-Reactive B Cells in Autoimmune BXD2 Mice

基于四聚体鉴定自身抗原反应性 B 细胞的通用方法:自身免疫性 BXD2 小鼠中 La 和 snRNP 反应性 B 细胞的表征

Jennie A Hamilton, Jun Li, Qi Wu, PingAr Yang, Bao Luo, Hao Li, John E Bradley, Justin J Taylor, Troy D Randall, John D Mountz, Hui-Chen Hsu

Interleukin-21 promotes germinal center reaction by skewing the follicular regulatory T cell to follicular helper T cell balance in autoimmune BXD2 mice

白细胞介素-21通过调节自身免疫性BXD2小鼠体内滤泡调节性T细胞与滤泡辅助性T细胞的平衡来促进生发中心反应。

Ding, Yanna; Li, Jun; Yang, PingAr; Luo, Bao; Wu, Qi; Zajac, Allan J; Wildner, Oliver; Hsu, Hui-Chen; Mountz, John D

Inhibition of fucosylation reshapes inflammatory macrophages and suppresses type II collagen-induced arthritis

抑制岩藻糖基化可重塑炎症巨噬细胞并抑制II型胶原诱导的关节炎

Li, Jun; Hsu, Hui-Chen; Ding, Yana; Li, Hao; Wu, Qi; Yang, PingAr; Luo, Bao; Rowse, Amber L; Spalding, David M; Bridges, S Louis Jr; Mountz, John D

IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells

IL-17RA 对滤泡 Th 细胞在生发中心亮区的最佳定位以促进自身抗体产生的 B 细胞至关重要

Yanna Ding, Jun Li, Qi Wu, Pingar Yang, Bao Luo, Shutao Xie, Kirk M Druey, Allan J Zajac, Hui-Chen Hsu, John D Mountz

Death receptor 5-targeted depletion of interleukin-23-producing macrophages, Th17, and Th1/17 associated with defective tyrosine phosphatase in mice and patients with rheumatoid arthritis.

死亡受体 5 靶向耗竭产生白细胞介素-23 的巨噬细胞、Th17 和 Th1/17,与小鼠和类风湿性关节炎患者中酪氨酸磷酸酶缺陷有关

Li Jun, Yang PingAr, Wu Qi, Li Hao, Ding Yanna, Hsu Hui-Chen, Spalding David M, Mountz John D

Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model

通过巨噬细胞耗竭和免疫调节治疗关节炎:在人源化死亡受体小鼠模型中测试凋亡介导的疗法

Jun Li, Hui-Chen Hsu, PingAr Yang, Qi Wu, Hao Li, Laura E Edgington, Matthew Bogyo, Robert P Kimberly, John D Mountz