日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthesis and Pharmacology of a Morphinan-Derived Dual Mu-Kappa Opioid Receptor Agonist Analgesic.

吗啡烷衍生的双重μ-κ阿片受体激动剂镇痛药的合成与药理学研究

Varga Balazs R, Uprety Rajendra, Paul Barnali, Knoll Alexis, Ramos-Gonzalez Nokomis, Appourchaux Kevin, Taylor Tori, Turgutalp Bengisu, Shinouchi Ryosuke, Eans Shainnel O, Williams Ashai K, Vasquez-Grinnell Steven G, Zaidi Saheem, Nazarova Antonina L, Varadi Andras, Le Rouzic Valerie, Brown Taylor G, Martinez Shani, Ansonoff Michael, Dardashti Rebecca Notis, Hunkele Amanda, Subrath Joan, Welch Matthew, Xu Jin, Rossi Grace C, Pintar John, Pasternak Gavril W, Katritch Vsevolod, McLaughlin Jay P, Pan Ying Xian, Majumdar Susruta

Exploring trust dynamics in health information systems: the impact of patients' health conditions on information source preferences

探索健康信息系统中的信任动态:患者健康状况对信息来源偏好的影响

Song, Mingming; Elson, Joel; Nguyen, Tin; Obasi, Sharon; Pintar, John; Bastola, Dhundy

Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine

阿片系统对氟西汀抗抑郁作用的贡献

Carazo-Arias, Elena; Nguyen, Phi T; Kass, Marley; Jee, Hyun Jung; Nautiyal, Katherine M; Magalong, Valerie; Coie, Lilian; Andreu, Valentine; Gergues, Mark M; Khalil, Huzefa; Akil, Huda; Arcego, Danusa Mar; Meaney, Michael; Anacker, Christoph; Samuels, Benjamin A; Pintar, John E; Morozova, Irina; Kalachikov, Sergey; Hen, Rene

Site selective C-H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy

帽柱木碱的位点选择性CH官能化揭示了一种调节阿片受体信号传导效力的分子开关

Bhowmik, Srijita; Galeta, Juraj; Havel, Václav; Nelson, Melissa; Faouzi, Abdelfattah; Bechand, Benjamin; Ansonoff, Mike; Fiala, Tomas; Hunkele, Amanda; Kruegel, Andrew C; Pintar, John E; Majumdar, Susruta; Javitch, Jonathan A; Sames, Dalibor

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

7-羟基帽柱木碱是帽柱木碱的活性代谢产物,也是其镇痛作用的关键介质。

Kruegel, Andrew C; Uprety, Rajendra; Grinnell, Steven G; Langreck, Cory; Pekarskaya, Elizabeth A; Le Rouzic, Valerie; Ansonoff, Michael; Gassaway, Madalee M; Pintar, John E; Pasternak, Gavril W; Javitch, Jonathan A; Majumdar, Susruta; Sames, Dalibor

Editorial: Current Perspectives on Insulin-Like Growth Factor Binding Protein (IGFBP) Research

社论:胰岛素样生长因子结合蛋白(IGFBP)研究的最新进展

Hoeflich, Andreas; Pintar, John; Forbes, Briony

Opioids and opioid receptors orchestrate wound repair

阿片类物质和阿片受体协调伤口修复

Wang, Ying; Gupta, Mihir; Poonawala, Tasneem; Farooqui, Mariya; Li, Yunfang; Peng, Fei; Rao, Sheldon; Ansonoff, Michael; Pintar, John E; Gupta, Kalpna

ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine

ProSAAS衍生的肽受可卡因调节,并且是可卡因运动效应敏化所必需的。

Berezniuk, Iryna; Rodriguiz, Ramona M; Zee, Michael L; Marcus, David J; Pintar, John; Morgan, Daniel J; Wetsel, William C; Fricker, Lloyd D

Mexneurin is a novel precursor of peptides in the central nervous system of rodents

Mexneurin是啮齿动物中枢神经系统中一种新型肽类前体。

Matus-Ortega, Maura E; Leff Gelman, Philippe; Calva-Nieves, Juan C; Flores-Zamora, Anabel; Salazar-Juárez, Alberto; Torner-Aguilar, Carlos-Alejandro; Gamba, Gerardo; De Los Heros, Paola; Peng, Bonnie; Pintar, John E; Gompf, Heinrich S; Allen, Charles N; Antón-Palma, Benito

Preclinical findings predicting efficacy and side-effect profile of LY2940094, an antagonist of nociceptin receptors

预测LY2940094(一种伤害感受素受体拮抗剂)疗效和副作用的临床前研究结果

Witkin, Jeffrey M; Rorick-Kehn, Linda M; Benvenga, Mark J; Adams, Benjamin L; Gleason, Scott D; Knitowski, Karen M; Li, Xia; Chaney, Steven; Falcone, Julie F; Smith, Janice W; Foss, Julie; Lloyd, Kirsti; Catlow, John T; McKinzie, David L; Svensson, Kjell A; Barth, Vanessa N; Toledo, Miguel A; Diaz, Nuria; Lafuente, Celia; Jiménez, Alma; Benito, Alfonso; Pedregal, Conception; Martínez-Grau, Maria A; Post, Anke; Ansonoff, Michael A; Pintar, John E; Statnick, Michael A