日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection

在 SARS-CoV-2 感染期间,改变的 ISGylation 驱动异常的巨噬细胞依赖性免疫反应

Deeksha Munnur #, Qiwen Teo #, Denzel Eggermont #, Horace H Y Lee #, Fabien Thery, Julian Ho, Sophie Wilhelmina van Leur, Wilson W S Ng, Lewis Y L Siu, Antje Beling, Hidde Ploegh, Adan Pinto-Fernandez, Andreas Damianou, Benedikt Kessler, Francis Impens, Chris Ka Pun Mok, Sumana Sanyal7

Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex

KRAS 致癌突变通过 CUL3/LZTR1 E3 连接酶复合物调节其周转

Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt M Kessler

Characterization and Evaluation of Human-Exoskeleton Interaction Dynamics: A Review

人体-外骨骼相互作用动力学的特征分析与评价:综述

Massardi, Stefano; Rodriguez-Cianca, David; Pinto-Fernandez, David; Moreno, Juan C; Lancini, Matteo; Torricelli, Diego

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity

去ISG化酶USP18的缺失增强了肿瘤细胞的抗原性和放射敏感性

Adan Pinto-Fernandez,Mariolina Salio,Tom Partridge,Jianzhou Chen,George Vere,Helene Greenwood,Cyriel Sebastiaan Olie,Andreas Damianou,Hannah Claire Scott,Henry Jack Pegg,Alessandra Chiarenza,Laura Díaz-Saez,Paul Smith,Claudia Gonzalez-Lopez,Bhavisha Patel,Emma Anderton,Neil Jones,Tim R Hammonds,Kilian Huber,Ruth Muschel,Persephone Borrow,Vincenzo Cerundolo,Benedikt M Kessler    0

USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma

USP28 缺失和小分子抑制剂可破坏 c-MYC 的稳定性并引起鳞状细胞肺癌的消退

E Josue Ruiz ,Adan Pinto-Fernandez ,Andrew P Turnbull ,Linxiang Lan ,Thomas M Charlton ,Hannah C Scott ,Andreas Damianou ,George Vere ,Eva M Riising ,Clive Da Costa ,Wojciech W Krajewski ,David Guerin ,Jeffrey D Kearns ,Stephanos Ioannidis ,Marie Katz ,Crystal McKinnon ,Jonathan O'Connell ,Natalia Moncaut ,Ian Rosewell ,Emma Nye ,Neil Jones ,Claire Heride ,Malte Gersch ,Min Wu ,Christopher J Dinsmore ,Tim R Hammonds ,Sunkyu Kim ,David Komander ,Sylvie Urbe ,Michael J Clague ,Benedikt M Kessler ,Axel Behrens

Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570: A Paradigmatic Example of Unspecific Protein Cross-linking with Michael Acceptor Motif-Containing Drugs

重新评估α,β-不饱和羰基DUB抑制剂b-AP15和VLX1570的作用机制:含迈克尔受体基序药物非特异性蛋白质交联的典型例子

Ward, Jennifer A; Pinto-Fernandez, Adan; Cornelissen, Loïc; Bonham, Sarah; Díaz-Sáez, Laura; Riant, Olivier; Huber, Kilian V M; Kessler, Benedikt M; Feron, Olivier; Tate, Edward W

USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation

USP30 为 PINK1-PARKIN 扩增线粒体泛素化设定触发阈值

Emma V Rusilowicz-Jones, Jane Jardine, Andreas Kallinos, Adan Pinto-Fernandez, Franziska Guenther, Mariacarmela Giurrandino, Francesco G Barone, Katy McCarron, Christopher J Burke, Alejandro Murad, Aitor Martinez, Elena Marcassa, Malte Gersch, Alexandre J Buckmelter, Katherine J Kayser-Bricker, Fred

Regulation of the endosomal SNX27-retromer by OTULIN

OTULIN 对内体 SNX27-逆转录酶的调控

Aurelia Stangl, Paul R Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T Pfluger, Farid El Oualid, Benedikt M Kessler, David Komander, Daniel Krappmann

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation

人类血小板蛋白泛素化及GPVI激活后的变化

Amanda J Unsworth, Izabela Bombik, Adan Pinto-Fernandez, Joanna F McGouran, Rebecca Konietzny, René P Zahedi, Steve P Watson, Benedikt M Kessler, Catherine J Pears

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting

去乙酰化抑制可逆转 PABPN1 依赖性肌肉萎缩

Cyriel S Olie, Muhammad Riaz, Rebecca Konietzny, Philip D Charles, Adan Pinto-Fernandez, Szymon M Kiełbasa, A Aartsma-Rus, Jelle J Goeman, Benedikt M Kessler, Vered Raz