日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis

抗沃尔巴克氏体药物AWZ1066S（一种氮杂喹唑啉类药物）与苯并咪唑类驱虫药联合使用，可产生协同作用，在丝虫病实验模型中于7天内达到灭菌和治愈效果。

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2024.1346068
Hegde, Shrilakshmi; Marriott, Amy E; Pionnier, Nicolas; Steven, Andrew; Bulman, Christina; Gunderson, Emma; Vogel, Ian; Koschel, Marianne; Ehrens, Alexandra; Lustigman, Sara; Voronin, Denis; Tricoche, Nancy; Hoerauf, Achim; Hübner, Marc P; Sakanari, Judy; Aljayyoussi, Ghaith; Gusovsky, Fabian; Dagley, Jessica; Hong, David W; O'Neill, Paul; Ward, Steven A; Taylor, Mark J; Turner, Joseph D
发表日期：2024
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A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi

利用小鼠感染模型和长期淋巴内皮细胞共培养系统评估抗马来布鲁氏丝虫成虫的药物

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0010474
Marriott, Amy E; Furlong Silva, Julio; Pionnier, Nicolas; Sjoberg, Hanna; Archer, John; Steven, Andrew; Kempf, Dale; Taylor, Mark J; Turner, Joseph D
炎症/感染
细胞生物学
内皮细胞
发表日期：2022
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Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis

四环素类药物通过干扰白细胞介素-4受体介导的淋巴管生成，改善实验性淋巴丝虫病病理。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI140853
Furlong-Silva, Julio; Cross, Stephen D; Marriott, Amy E; Pionnier, Nicolas; Archer, John; Steven, Andrew; Merker, Stefan Schulte; Mack, Matthias; Hong, Young-Kwon; Taylor, Mark J; Turner, Joseph D
信号转导
细胞生物学
发表日期：2021
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The insufficiency of circulating miRNA and DNA as diagnostic tools or as biomarkers of treatment efficacy for Onchocerca volvulus.

循环 miRNA 和 DNA 作为诊断工具或治疗效果生物标志物在诊断盘尾丝虫病方面存在不足

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-020-63249-4
Macfarlane Cara L, Quek Shannon, Pionnier Nicolas, Turner Joseph D, Wanji Samuel, Wagstaff Simon C, Taylor Mark J
miRNA
发表日期：2020
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Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling

嗜酸性粒细胞介导的对成虫丝虫感染的免疫控制可以在没有IL-4受体信号传导的情况下进行

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.1901244
Pionnier, Nicolas; Sjoberg, Hanna; Furlong-Silva, Julio; Marriott, Amy; Halliday, Alice; Archer, John; Steven, Andrew; Taylor, Mark J; Turner, Joseph D
IL-4
信号转导
粒细胞
免疫/内分泌
细胞生物学
炎症/感染
发表日期：2020
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Generation of Loa loa infective larvae by experimental infection of the vector, Chrysops silacea

通过实验感染媒介昆虫 Chrysops silacea 来产生罗阿丝虫感染性幼虫

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0008415
Ndzeshang, Lontum B; Fombad, Fanny F; Njouendou, Abdel J; Chunda, Valerine C; Gandjui, Narcisse V T; Akumtoh, Desmond N; Chounna, Patrick W N; Steven, Andrew; Pionnier, Nicolas P; Layland, Laura E; Ritter, Manuel; Hoerauf, Achim; Taylor, Mark J; Turner, Joseph D; Wanji, Samuel
炎症/感染
发表日期：2020
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Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

在小鼠感染模型中，短期口服氟苯达唑对盘尾丝虫成虫雄性或布鲁氏丝虫微丝蚴没有显著疗效。

期刊:PLoS Neglected Tropical Diseases
影响因子:3.4
doi:10.1371/journal.pntd.0006356
Sjoberg, Hanna T; Pionnier, Nicolas; Aljayyoussi, Ghaith; Metuge, Haelly M; Njouendou, Abdel J; Chunda, Valerine C; Fombad, Fanny F; Tayong, Dizzle B; Gandjui, Narcisse V T; Akumtoh, Desmond N; Chounna, Patrick W N; Ndzeshang, Bertrand L; Lachaud, Sophie; Tekle, Fetene; Quirynen, Ludo; Engelen, Marc; Baeten, Benny; Steven, Andrew; Ward, Stephen A; Taylor, Mark J; Wanji, Samuel; Turner, Joseph D
炎症/感染
发表日期：2019
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Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

白细胞介素-4激活的巨噬细胞通过维持CCR3依赖性嗜酸性粒细胞增多症来介导对丝虫感染的免疫力

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1006949
Turner Joseph D, Pionnier Nicolas, Furlong-Silva Julio, Sjoberg Hanna, Cross Stephen, Halliday Alice, Guimaraes Ana F, Cook Darren A N, Steven Andrew, Van Rooijen Nico, Allen Judith E, Jenkins Stephen J, Taylor Mark J
细胞生物学
发表日期：2018
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Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis

短期高剂量利福平治疗可使沃尔巴克氏体耗竭，这可预测淋巴丝虫病和盘尾丝虫病临床前模型的治愈结果。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-00322-5
Aljayyoussi, Ghaith; Tyrer, Hayley E; Ford, Louise; Sjoberg, Hanna; Pionnier, Nicolas; Waterhouse, David; Davies, Jill; Gamble, Joanne; Metuge, Haelly; Cook, Darren A N; Steven, Andrew; Sharma, Raman; Guimaraes, Ana F; Clare, Rachel H; Cassidy, Andrew; Johnston, Kelly L; Myhill, Laura; Hayward, Laura; Wanji, Samuel; Turner, Joseph D; Taylor, Mark J; Ward, Stephen A
发表日期：2017
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