日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Improving Measures of Chemical Structural Similarity Using Machine Learning on Chemical-Genetic Interactions

利用机器学习改进化学-遗传相互作用中化学结构相似性度量

Safizadeh, Hamid; Simpkins, Scott W; Nelson, Justin; Li, Sheena C; Piotrowski, Jeff S; Yoshimura, Mami; Yashiroda, Yoko; Hirano, Hiroyuki; Osada, Hiroyuki; Yoshida, Minoru; Boone, Charles; Myers, Chad L

Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments

利用 BEAN-counter 对多重条形码测序实验中的基因互作进行量化

Simpkins, Scott W; Deshpande, Raamesh; Nelson, Justin; Li, Sheena C; Piotrowski, Jeff S; Ward, Henry Neil; Yashiroda, Yoko; Osada, Hiroyuki; Yoshida, Minoru; Boone, Charles; Myers, Chad L

Resistance against Sclerotinia sclerotiorum in soybean involves a reprogramming of the phenylpropanoid pathway and up-regulation of antifungal activity targeting ergosterol biosynthesis

大豆对核盘菌的抗性涉及苯丙烷类代谢途径的重编程和靶向麦角甾醇生物合成的抗真菌活性的上调。

Ranjan, Ashish; Westrick, Nathaniel M; Jain, Sachin; Piotrowski, Jeff S; Ranjan, Manish; Kessens, Ryan; Stiegman, Logan; Grau, Craig R; Conley, Shawn P; Smith, Damon L; Kabbage, Mehdi

Chemical genomic guided engineering of gamma-valerolactone tolerant yeast.

利用化学基因组学方法改造耐γ-戊内酯酵母

Bottoms Scott, Dickinson Quinn, McGee Mick, Hinchman Li, Higbee Alan, Hebert Alex, Serate Jose, Xie Dan, Zhang Yaoping, Coon Joshua J, Myers Chad L, Landick Robert, Piotrowski Jeff S

Functional annotation of chemical libraries across diverse biological processes

对化学库在不同生物过程中的功能进行注释

Piotrowski, Jeff S; Li, Sheena C; Deshpande, Raamesh; Simpkins, Scott W; Nelson, Justin; Yashiroda, Yoko; Barber, Jacqueline M; Safizadeh, Hamid; Wilson, Erin; Okada, Hiroki; Gebre, Abraham A; Kubo, Karen; Torres, Nikko P; LeBlanc, Marissa A; Andrusiak, Kerry; Okamoto, Reika; Yoshimura, Mami; DeRango-Adem, Eva; van Leeuwen, Jolanda; Shirahige, Katsuhiko; Baryshnikova, Anastasia; Brown, Grant W; Hirano, Hiroyuki; Costanzo, Michael; Andrews, Brenda; Ohya, Yoshikazu; Osada, Hiroyuki; Yoshida, Minoru; Myers, Chad L; Boone, Charles

Mutations That Alter the Bacterial Cell Envelope Increase Lipid Production.

改变细菌细胞包膜的突变会增加脂质的产生

Lemmer Kimberly C, Zhang Weiping, Langer Samantha J, Dohnalkova Alice C, Hu Dehong, Lemke Rachelle A, Piotrowski Jeff S, Orr Galya, Noguera Daniel R, Donohue Timothy J

Coculture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin

海洋无脊椎动物相关细菌的共培养及跨学科技术促成了新型抗生素——凯伊辛的生物合成与发现。

Adnani, Navid; Chevrette, Marc G; Adibhatla, Srikar N; Zhang, Fan; Yu, Qing; Braun, Doug R; Nelson, Justin; Simpkins, Scott W; McDonald, Bradon R; Myers, Chad L; Piotrowski, Jeff S; Thompson, Christopher J; Currie, Cameron R; Li, Lingjun; Rajski, Scott R; Bugni, Tim S

Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin

海洋来源抗梭菌药物埃克替霉素的化学基因组学、结构解析和体内研究

Wyche, Thomas P; Alvarenga, René F Ramos; Piotrowski, Jeff S; Duster, Megan N; Warrack, Simone R; Cornilescu, Gabriel; De Wolfe, Travis J; Hou, Yanpeng; Braun, Doug R; Ellis, Gregory A; Simpkins, Scott W; Nelson, Justin; Myers, Chad L; Steele, James; Mori, Hirotada; Safdar, Nasia; Markley, John L; Rajski, Scott R; Bugni, Tim S

Mechanism of imidazolium ionic liquids toxicity in Saccharomyces cerevisiae and rational engineering of a tolerant, xylose-fermenting strain.

咪唑离子液体对酿酒酵母的毒性机制及耐受性木糖发酵菌株的合理工程设计

Dickinson Quinn, Bottoms Scott, Hinchman Li, McIlwain Sean, Li Sheena, Myers Chad L, Boone Charles, Coon Joshua J, Hebert Alexander, Sato Trey K, Landick Robert, Piotrowski Jeff S

Correction: Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

更正:定向进化揭示了意想不到的上位性相互作用,这些相互作用改变了代谢调控并使酿酒酵母能够利用厌氧木糖

Sato, Trey K; Tremaine, Mary; Parreiras, Lucas S; Hebert, Alexander S; Myers, Kevin S; Higbee, Alan J; Sardi, Maria; McIlwain, Sean J; Ong, Irene M; Breuer, Rebecca J; Narasimhan, Ragothaman Avanasi; McGee, Mick A; Dickinson, Quinn; La Reau, Alex; Xie, Dan; Tian, Mingyuan; Piotrowski, Jeff S; Reed, Jennifer L; Zhang, Yaoping; Coon, Joshua J; Hittinger, Chris Todd; Gasch, Audrey P; Landick, Robert