日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

对放射免疫疗法的不同反应是由肿瘤微环境的内在特征决定的。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010405
Gadwa, Jacob; Yu, Justin; Piper, Miles; Knitz, Michael W; Darragh, Laurel B; Olimpo, Nicholas; Corbo, Sophia; Beynor, Jessica I; Neupert, Brooke; Nguyen, Alexander T; Hodgson, Chloe; Nguyen, Diemmy; Abdelazeem, Khalid Nm; Saviola, Anthony; Pousse, Laurene; Bransi, Ali; Pincha, Mudita; Klein, Christian; Amann, Maria; Karam, Sana D
肿瘤
肿瘤微环境
肿瘤免疫
免疫/内分泌
发表日期：2025
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IL15/IL15Rα complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to induce expansion of progenitor TCF1+ CD8 T cells

IL15/IL15Rα复合物仅在缺乏调节性T细胞（Tregs）的情况下才能在放射治疗后诱导抗肿瘤免疫反应，并且不能诱导祖细胞TCF1+ CD8 T细胞的扩增。

期刊:
影响因子:
doi:10.1101/2024.09.18.613691
Piper, Miles; Gadwa, Jacob; Hodgson, Chloe; Knitz, Michael; Yee, Elliott; Zhu, Yuwen; Larson, Keira Y; Klein, Christian; Amann, Maria; Saviola, Anthony; Karam, Sana D
肿瘤
T细胞
肿瘤免疫
CD8
Treg
T细胞
细胞生物学
免疫/内分泌
发表日期：2024
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Vasculitis, CA19-9, and Perineural Invasion Differentially Predict Response and Surgical Outcome in Pancreatic Ductal Adenocarcinoma

血管炎、CA19-9 和神经周围浸润对胰腺导管腺癌的治疗反应和手术结果具有不同的预测价值

期刊:International Journal of Radiation Oncology Biology Physics
影响因子:6.5
doi:10.1016/j.ijrobp.2022.12.039
Piper, Miles; Ross, Richard Blake; Hu, Junxiao; Watanabe, Shuichi; Knitz, Michael; Mehrotra, Sanjana; Shulick, Richard; Chiaro, Marco Del; Karam, Sana D
肿瘤
肿瘤免疫
发表日期：2023
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Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.

胰腺导管腺癌细胞通过调节 NLRP3 激活来产生耐受性微环境

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-23-0065
Amo-Aparicio Jesus, Dominguez Adrian, Atif Shaikh M, Dinarello Alberto, Azam Tania, Alula Kibrom M, Piper Miles, Lieu Christopher H, Lentz Robert W, Leal Alexis D, Bagby Stacey M, Messersmith Wells A, Karam Sana D, Dinarello Charles A, Pitts Todd M, Marchetti Carlo
细胞生物学
发表日期：2023
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Dichotomous effects of cellular expression of STAT3 on tumor growth of HNSCC

STAT3细胞表达对头颈部鳞状细胞癌肿瘤生长的双重影响

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2021.11.011
Bickett, Thomas E; Knitz, Michael W; Piper, Miles; Oweida, Ayman J; Gadwa, Jacob; Darragh, Laurel B; Nguyen, Diemmy; Bhatia, Shilpa; Bhuvane, Shiv; Phan, Andy V; Van Court, Benjamin; Corbo, Sophia; Pham, Tiffany; Dent, Alexander L; Lenz, Laurel; Karam, Sana D
肿瘤
肿瘤免疫
JAK/STAT
STAT3
细胞生物学
发表日期：2022
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Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma

靶向 Treg 表达的 STAT3 可增强 NK 细胞介导的转移监测并改善胰腺腺癌的治疗反应

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-21-2767
Piper, Miles; Van Court, Benjamin; Mueller, Adam; Watanabe, Shuichi; Bickett, Thomas; Bhatia, Shilpa; Darragh, Laurel B; Mayeda, Max; Nguyen, Diemmy; Gadwa, Jacob; Knitz, Michael; Corbo, Sophia; Morgan, Rustain; Lee, Jung-Jae; Dent, Alexander; Goodman, Karyn; Messersmith, Wells; Schulick, Richard; Del Chiaro, Marco; Zhu, Yuwen; Kedl, Ross M; Lenz, Laurel; Karam, Sana D
肿瘤
T细胞
肿瘤免疫
JAK/STAT
STAT3
Treg
细胞生物学
NK 细胞
发表日期：2022
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FLT3L Release by Natural Killer Cells Enhances Response to Radioimmunotherapy in Preclinical Models of HNSCC

自然杀伤细胞释放的FLT3L可增强头颈部鳞状细胞癌临床前模型中放射免疫疗法的疗效

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-21-0971
Bickett, Thomas E; Knitz, Michael; Darragh, Laurel B; Bhatia, Shilpa; Van Court, Benjamin; Gadwa, Jacob; Bhuvane, Shiv; Piper, Miles; Nguyen, Diemmy; Tu, Hua; Lenz, Laurel; Clambey, Eric T; Barry, Kevin; Karam, Sana D
肿瘤
肿瘤免疫
FLT3
FLT3L
自然杀伤细胞
细胞生物学
免疫/内分泌
发表日期：2021
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Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide

利用STAT3反义寡核苷酸抑制髓系来源的抑制细胞可增强胰腺导管腺癌对放射治疗的反应。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-020-02701-w
Oweida, Ayman J; Mueller, Adam C; Piper, Miles; Milner, Dallin; Van Court, Benjamin; Bhatia, Shilpa; Phan, Andy; Bickett, Thomas; Jordan, Kimberly; Proia, Theresa; Schulick, Richard; Messersmith, Wells A; Del Chiaro, Marco; Clambey, Eric; Gough, Michael J; Williams, Jason; Hansen, Kirk; Goodman, Karyn; Karam, Sana D
STAT3
JAK/STAT
肿瘤
细胞生物学
肿瘤免疫
发表日期：2021
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The interplay between cancer associated fibroblasts and immune cells in the context of radiation therapy

放射治疗背景下癌症相关成纤维细胞与免疫细胞之间的相互作用

期刊:Molecular Carcinogenesis
影响因子:3.2
doi:10.1002/mc.23205
Piper, Miles; Mueller, Adam C; Karam, Sana D
成纤维细胞
肿瘤
肿瘤免疫
细胞生物学
免疫/内分泌
发表日期：2020
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